Intensive Daily Measurement of Simultaneous Alcohol and Marijuana Use in a High-Risk Community Sample of Young Adults: Impacts on Acute and Longer-term Use and Consequences

对高风险社区年轻人样本中同时使用酒精和大麻的每日强化测量：对急性和长期使用的影响及后果

• 批准号: 9753831
• 负责人: CHRISTINE M. Lee
• 金额: $ 48.3万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-08-01 至 2021-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9753831
• 关键词: 21 year old; Acute; Address; Adult; Affect; Alaska; Alcohol consumption; Alcohol or Other Drugs use; Alcohols; Area; Attention; Attitude; Behavioral; Car Phone; Colorado; Communities; Consequentialism; Data; Data Analytics; District of Columbia; Driving While Intoxicated; Feeling; Gender; Health; Health Care Costs; High Prevalence; Individual; Injury; Intoxication; Knowledge; Lead; Legal; Marijuana; Measurement; Mental Health; Modeling; Motivation; National Institute on Alcohol Abuse and Alcoholism; Oregon; Pattern; Perception; Policies; Population; Prevalence; Public Health; Reporting; Risk; Sampling; Statutes and Laws; Techniques; Testing; Time; Traffic accidents; United States; Voice; Washington; Youth; aged; alcohol consequences; alcohol research; automobile accident; base; binge drinking; college; coping; demographics; drinking; hangover; high risk; intervention program; marijuana legalization; marijuana use; marijuana user; physical conditioning; public policy on alcohol; response; risk perception; social; therapy design; young adult

ABSTRACT Major changes in marijuana legislation are likely to affect not only the use of marijuana, but also the use of other substances including alcohol. Alcohol and marijuana are psychoactive substances commonly used by young adults in the US and are independently associated with numerous acute and long-term consequences. To date, recreational marijuana use has been legalized for adults age 21+ in four states (Washington, Colorado, Oregon, and Alaska) and the District of Columbia, with numerous states currently debating similar legislation. These policy changes have shifted attention to the important individual and public health implications of simultaneous alcohol and marijuana (SAM) use, and potential additive or synergistic negative effects and consequences (e.g., increased risk of driving while intoxicated, fatal car accidents). Among youth and adults, clear patterns are emerging; perceptions of the harmfulness of marijuana use are decreasing and the prevalence of marijuana use is increasing. Further, it is clear that SAM use is common among youth and young adults. Given the public health costs associated with alcohol use, there is a pressing need to understand the ways in which SAM use may have complementary effects (both alcohol and marijuana use increase) or substitution effects (amount of alcohol use decreases when used with marijuana), as well as the extent to which SAM use is associated with increases in acute and longer-term consequences of alcohol use. To date, very little is known regarding how SAM use differs from use of either substance alone on a given occasion. The current application proposes to collect and analyze intensive data collected twice daily via mobile phones for 16 weeks (using interactive voice response) across two years and longitudinal data collected annually online across three years from a high-risk community sample of young adult SAM users, aged 18-25, in the state of Washington. Specific aims of this application are to: 1) examine whether SAM use poses additional alcohol- related risks, compared to using alcohol without marijuana, at the daily level; 2) understand the motivations, intentions, and situations that make SAM use more likely and more consequential among young adults; 3) model the longitudinal patterns of SAM use and associations with health consequences across 3 years; and 4) examine potential moderators of these relationships. The proposed study will examine SAM use in a state where marijuana is legal and the observed effects will add knowledge about the effects of marijuana on alcohol use and related health consequences among young adults in the US.

抽象的 大麻立法的重大变化不仅可能影响大麻的使用，而且会影响 其他物质在内。酒精和大麻是通常使用的精神活性物质 美国的年轻人与许多急性和长期后果独立相关。 迄今为止，在四个州的21岁以上的成年人合法化休闲大麻 科罗拉多州，俄勒冈州和阿拉斯加）和哥伦比亚特区，目前有许多州的辩论类似 立法。这些政策变化已将注意力转移到重要的个人和公共卫生上 同时酒精和大麻（SAM）的含义以及潜在的添加剂或协同负面 影响和后果（例如，醉酒，致命的汽车事故的驾驶风险增加）。在青年中 成年人，明确的模式正在出现；对大麻使用有害性的看法正在减少，并且 大麻使用的患病率正在增加。此外，很明显，SAM在青年中使用很常见 年轻人。鉴于与酒精使用相关的公共卫生费用，有迫切需要了解 SAM使用的方式可能具有互补的影响（酒精和大麻使用量增加）或 替代效应（与大麻一起使用时的饮酒量减少），以及 SAM的使用与饮酒的急性和长期后果的增加有关。迄今为止， 关于SAM在给定场合使用与单独使用任何一种物质的不同之处，知之甚少。这 当前申请建议通过手机收集和分析两次收集的密集数据 在两年内进行16周（使用交互式语音响应），每年在线收集纵向数据 在三年的高风险社区样本中，年轻的成年SAM用户（18-25岁）处于 华盛顿。该应用的具体目的是：1）检查SAM使用是否添加其他酒精 - 与每天使用无大麻的酒精相比，相关风险； 2）了解动机， 在年轻人中，意图和使SAM使用更有可能和更大的情况； 3） 在3年中对SAM使用的纵向模式进行建模；和4） 检查这些关系的潜在主持人。拟议的研究将检查SAM在一个州的使用 大麻是合法的，观察到的影响将增加有关大麻对酒精影响的知识 美国年轻人的使用及相关的健康后果。