Vascular Biology and Human Disease: From Molecular Pathways to Novel Therapies
血管生物学和人类疾病:从分子途径到新疗法
基本信息
- 批准号:9471548
- 负责人:
- 金额:$ 1.38万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2018
- 资助国家:美国
- 起止时间:2018-01-01 至 2018-12-31
- 项目状态:已结题
- 来源:
- 关键词:AddressAdultArteriesBiologyBlood VesselsClinical TrialsCollaborationsDataDisciplineDiseaseEmbryonic DevelopmentEndothelial CellsFutureHeterogeneityHumanImmunologistIndustrializationInvestigationKnowledgeLinkLymphaticLymphatic EndotheliumMalignant NeoplasmsMolecularNew MexicoOrganPathologicPathologyPathway interactionsPropertyResearchScientistSignal PathwayStimulusSystemTherapeuticTimeVascular DiseasesVascular SystemVeinsVenousclinical implementationendothelial dysfunctionhuman diseaseimprovedmeetingsmultidisciplinarynew technologynovelnovel therapeutic interventionnovel therapeuticsresponsesymposiumtool
项目摘要
ABSTRACT
Support is requested for a Keystone Symposia conference entitled Vascular Biology and Human Diseases:
From Molecular Pathways to Novel Therapeutics, organized by Drs. Elisabetta Dejana, Anne C. Eichmann and
Gavin O. Thurston. The conference will be held in Santa Fe, New Mexico from February 25 – March 1, 2018.
Recent years have seen rapid progress in our knowledge of how the vascular system is formed during embryo
development and in adults expressing in proliferative diseases such as cancer. It has become unequivocally
evident that endothelial cells express highly specific and distinct functions in arteries, veins and lymphatics.
Moreover, endothelial cells are able to further modify their functional properties in order to meet the specific
needs of the different organs. This meeting will address the mechanisms that orchestrate organ-specific
endothelial differentiation, making a connection between endothelial dysfunction and organ pathology. The
major challenge will be to link our experimental knowledge to the understanding of human vascular diseases.
The symposium will bring together teams of vascular biologists, neuroscientists, immunologists and clinicians
from all over the world to share their recent discoveries and to direct future efforts to find novel and more
precise therapies.
摘要
要求为题为“血管生物学和人类疾病:
从分子途径到新型治疗,由Elisabetta Dejana博士,Anne C.艾希曼和
加文·奥瑟斯顿会议将于2018年2月25日至3月1日在新墨西哥州圣达菲举行。
近年来,我们对胚胎期血管系统如何形成的认识有了迅速的进展
在发育和成人中表达,在增殖性疾病如癌症中表达。它已经明确地成为
显然,内皮细胞在动脉、静脉和血管中表达高度特异性和独特的功能。
此外,内皮细胞能够进一步改变其功能特性,以满足特定的细胞功能。
不同器官的需求。本次会议将解决的机制,编排器官特异性
内皮分化,使内皮功能障碍和器官病理学之间的连接。的
主要的挑战将是将我们的实验知识与对人类血管疾病的理解联系起来。
研讨会将汇集血管生物学家、神经科学家、免疫学家和临床医生的团队
来自世界各地的科学家分享他们最近的发现,并指导未来的努力,以发现新的和更多的
精确的治疗
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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{{ truncateString('Thale Cross Jarvis', 18)}}的其他基金
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自噬和神经退行性变:治疗机制
- 批准号:
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- 资助金额:
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