The Human Microbiome: Ecology and Evolution

人类微生物组：生态学与进化

• 批准号: 10391370
• 负责人: Thale Cross Jarvis
• 金额: $ 0.5万
• 依托单位: KEYSTONE SYMPOSIA
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-01-20 至 2022-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10391370
• 关键词: Bacteriophages; Binding; Biological Models; Canada; Collaborations; Demographer; Disease; Ecology; Educational workshop; Environment; Evolution; Genetic; Health; Health Promotion; Human; Human Microbiome; Joints; Knowledge; Learning; Link; Methodology; Modernization; Molecular; Movement; Organ; Outcome; Pattern; Population; Process; Research; Research Personnel; Scientist; Shapes; System; Thinking; Time; Work; antimicrobial; clinical practice; design; emerging antimicrobial resistance; gut microbiome; host microbiome; host-microbe interactions; insight; microbial; microbiome; microbiome research; microbiota; molecular scale; new therapeutic target; next generation; novel strategies; posters; programs; stressor; symposium; theories

ABSTRACT Support is requested for a Keystone Symposia conference entitled The Human Microbiome: Ecology and Evolution, organized by Drs. Ruth E. Ley, Alejandro Reyes and C. Jessica Metcalf. The conference will be held in Banff, Canada from February 13-16, 2022. This Keystone Symposia conference will explore the evolutionary and ecological forces shaping the interplay between the human host and microbiome. The microbiome is implicated in a widening set of disease conditions, yet many questions remain as to how its diversity and composition are assembled and maintained. This program is designed to take on the topic of the microbiome across scales, integrating the latest understanding of human microbiome diversity across time and space, and delving into the molecular interactions that shape the associations. This conference aims to understand how movement of human populations, past and present, shape patterns of microbiome diversity. The program will include sessions on deciphering evolutionary dynamics linking microbiota to the human host, as well as discussions on understanding the co-evolution of humans with the microbiome at level of interactions at the molecular scale. Other topics will assess how interactions between host and microbiome can be harnessed for health. Through integration of patterns, processes and theory derived from human and non-human systems, attendees will gain an integrated view of microbiome diversity across modern human populations, and their interactions in host health.

抽象的 请求支持Keystone研讨会会议，标题为“人类微生物组：生态学”和 进化，由Drs组织。露丝·E·莱伊（Ruth E.会议将是 从2022年2月13日至16日在加拿大班夫举行。 这次Keystone研讨会会议将探讨塑造相互作用的进化和生态力量 在人类宿主和微生物组之间。微生物组与一组扩大的疾病有关 条件但是，关于其多样性和组成如何组装和维护的许多问题仍然存在。 该程序旨在在范围内介绍微生物组的主题，并集成了最新的 了解跨时空的人类微生物组多样性，并深入研究分子 塑造关联的相互作用。这次会议旨在了解人类的运动 过去和现在的种群，微生物组多样性的形状模式。该程序将包括会议 解密的进化动力学将微生物群与人宿主联系起来，并讨论 了解人类与微生物组在相互作用水平上以分子尺度的共同进化。 其他主题将评估宿主和微生物组之间的相互作用如何用于健康。通过 来自人类和非人类系统的模式，过程和理论的整合，与会者将获得 对现代人类种群的微生物组多样性的综合观点及其在宿主中的互动 健康。