The Human Microbiome: Ecology and Evolution

摘要 要求为题为“人类微生物组：生态学和生物学”的Keystone专题讨论会提供支助。 进化论，由博士露丝E。Ley，Alejandro Reyes和C.杰西卡·梅特卡夫会议将 2022年2月13日至16日在加拿大班夫举行。 本次Keystone研讨会将探讨塑造相互作用的进化和生态力量 人类宿主和微生物之间的联系微生物组与一系列不断扩大的疾病有关 尽管如此，在如何组合和维持其多样性和组成方面仍存在许多问题。 该计划旨在探讨跨尺度微生物组的主题，整合最新的 了解人类微生物组在时间和空间上的多样性，并深入研究 形成关联的互动。本次会议旨在了解人类运动是如何 过去和现在的人口塑造了微生物组多样性的模式。该方案将包括会议上， 破译微生物与人类宿主之间的进化动力学，以及关于 了解人类与微生物组在分子尺度相互作用水平上的共同进化。 其他主题将评估如何利用宿主和微生物组之间的相互作用促进健康。通过 整合模式，流程和理论来自人类和非人类系统，与会者将获得 对现代人群中微生物组多样性及其在宿主中的相互作用的综合看法 健康

ABSTRACT Support is requested for a Keystone Symposia conference entitled The Human Microbiome: Ecology and Evolution, organized by Drs. Ruth E. Ley, Alejandro Reyes and C. Jessica Metcalf. The conference will be held in Banff, Canada from February 13-16, 2022. This Keystone Symposia conference will explore the evolutionary and ecological forces shaping the interplay between the human host and microbiome. The microbiome is implicated in a widening set of disease conditions, yet many questions remain as to how its diversity and composition are assembled and maintained. This program is designed to take on the topic of the microbiome across scales, integrating the latest understanding of human microbiome diversity across time and space, and delving into the molecular interactions that shape the associations. This conference aims to understand how movement of human populations, past and present, shape patterns of microbiome diversity. The program will include sessions on deciphering evolutionary dynamics linking microbiota to the human host, as well as discussions on understanding the co-evolution of humans with the microbiome at level of interactions at the molecular scale. Other topics will assess how interactions between host and microbiome can be harnessed for health. Through integration of patterns, processes and theory derived from human and non-human systems, attendees will gain an integrated view of microbiome diversity across modern human populations, and their interactions in host health.