The Human Microbiome: Ecology and Evolution

人类微生物组：生态学与进化

• 批准号: 10391370
• 负责人: Thale Cross Jarvis
• 金额: $ 0.5万
• 依托单位: KEYSTONE SYMPOSIA
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-01-20 至 2022-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10391370
• 关键词: Bacteriophages; Binding; Biological Models; Canada; Collaborations; Demographer; Disease; Ecology; Educational workshop; Environment; Evolution; Genetic; Health; Health Promotion; Human; Human Microbiome; Joints; Knowledge; Learning; Link; Methodology; Modernization; Molecular; Movement; Organ; Outcome; Pattern; Population; Process; Research; Research Personnel; Scientist; Shapes; System; Thinking; Time; Work; antimicrobial; clinical practice; design; emerging antimicrobial resistance; gut microbiome; host microbiome; host-microbe interactions; insight; microbial; microbiome; microbiome research; microbiota; molecular scale; new therapeutic target; next generation; novel strategies; posters; programs; stressor; symposium; theories

ABSTRACT Support is requested for a Keystone Symposia conference entitled The Human Microbiome: Ecology and Evolution, organized by Drs. Ruth E. Ley, Alejandro Reyes and C. Jessica Metcalf. The conference will be held in Banff, Canada from February 13-16, 2022. This Keystone Symposia conference will explore the evolutionary and ecological forces shaping the interplay between the human host and microbiome. The microbiome is implicated in a widening set of disease conditions, yet many questions remain as to how its diversity and composition are assembled and maintained. This program is designed to take on the topic of the microbiome across scales, integrating the latest understanding of human microbiome diversity across time and space, and delving into the molecular interactions that shape the associations. This conference aims to understand how movement of human populations, past and present, shape patterns of microbiome diversity. The program will include sessions on deciphering evolutionary dynamics linking microbiota to the human host, as well as discussions on understanding the co-evolution of humans with the microbiome at level of interactions at the molecular scale. Other topics will assess how interactions between host and microbiome can be harnessed for health. Through integration of patterns, processes and theory derived from human and non-human systems, attendees will gain an integrated view of microbiome diversity across modern human populations, and their interactions in host health.

摘要 请求支助题为《人类微生物组：生态学和 进化论，由Ruth E.Ley博士、Alejandro Reyes博士和C.Jessica Metcalf博士组织。会议将于 2022年2月13日至16日在加拿大班夫举行。 本次Keystone研讨会将探讨形成相互作用的进化和生态力量 在人类宿主和微生物群之间。微生物组与一系列扩大的疾病有关 然而，关于如何组合和保持其多样性和组成，仍然存在许多问题。 该计划旨在跨规模地讨论微生物组的主题，整合最新的 了解跨越时间和空间的人类微生物群落多样性，并深入研究分子 塑造这种联系的相互作用。这次会议的目的是了解人类运动 过去和现在的种群塑造了微生物群多样性的格局。该计划将包括以下课程： 破译将微生物区系与人类宿主联系起来的进化动力学，以及关于 在分子水平上理解人类与微生物群的共同进化。 其他主题将评估如何利用宿主和微生物群之间的相互作用来促进健康。穿过 整合来自人类和非人类系统的模式、流程和理论，与会者将获得 现代人类种群中微生物群多样性及其在宿主中相互作用的综合观点 健康。