How do stem cells get specified during embryonic muscle development?
How do stem cells get specified during embryonic muscle development?
批准号:
DP240101647
负责人:
Prof Peter Currie
金额:
$44.26万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Discovery Projects
财政年份:
2024
资助国家:
澳大利亚
项目状态:
未结题
起止时间:
2024-01-01 至 2026-12-31
中文摘要
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英文摘要
This project aims to investigate the mechanisms by which muscle stem cells first form in the embryo. This project expects to generate new knowledge on the mechanism that patterns cell types in the embryonic myotome. Expected outcomes of this project include uncovering the developmental mechanisms of cell type specification in the myotome with specific reference to the generation of stem cells. This should provide significant benefits as it will inform how long lived tissue resident stem cells can be made in the first instance, knowledge that is critical for making stem cells on demand outside the animal and manipulating stem cells in living tissue.
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