Tissue microenvironment (TiMe) training program

组织微环境（TiMe）培训计划

• 批准号: 9458180
• 负责人: Rohit Bhargava
• 金额: $ 17.13万
• 依托单位: UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-04-01 至 2021-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9458180
• 关键词: Tissues; Training Programs

 DESCRIPTION (provided by applicant): Tissue Microenvironment Training Program (T32) Project Summary/Abstract A quantitative understanding of the tissue microenvironment (TiMe) is now recognized as critical for advancing biomedical science and healthcare, ranging from regenerative medicine to managing the burden of cancer. To this end, the integration of three technological approaches is essential: (a) sensing and imaging to measure biochemical and biophysical parameters, (b) bioengineering to recapitulate the TiMe, and (c) computational modeling to develop the next generation of productive scientific leaders. Accordingly, we propose a unique educational platform in which predoctoral students will integrate the use of the three technological approaches in TiMe-related studies using the biological contexts of disease and development. With intensive mentoring and systematic activities focused on professional development, trainees will become the next generation of interdisciplinary leaders capable of undertaking fundamental research and enabling translational advances. The University of Illinois at Urbana-Champaign has exceptionally strong disciplinary programs, diverse faculty spanning the intellectual arc of the program, and appropriate facilities and unique resources in each of these technological areas. The Training Program is distinctly advantaged by our strong history of successful graduate training, including a commitment to diversity and individuals with disabilities, a culture of productive collaboration, a new Department of Bioengineering, and strong institutional support. Thirty-nine faculty, many of whom are currently collaborating in TiMe research, will serve as faculty mentors. At least eight trainees will be supported for up to two years each. NIH-supported trainees (4), augmented by University support for additional trainees (4, ramping up to 5 in year 3), will be drawn from a strong applicant pool across campus. Training will include four core components-Curricular Activities to ensure depth in the three technological areas and apposite breadth across disciplines, Extracurricular Activities to develop pragmatic skills, Professional Development to empower trainees to become research leaders, and Career Development to ensure trainees make lifelong contributions to society. The activities will be structured in a manner to streamline education, allowing the students to focus efficiently on research, and the awarded doctoral degree will include a special designation (concentration in TiMe). Traditional education will further be enhanced by co- mentored research with possibilities of translational opportunities via a new engineering-based College of Medicine. Outcomes will be rigorously evaluated throughout the program to improve training, to guide administrative decision-making and to disseminate best practices. The vision, expertise, and infrastructure of the Illinois TiMe Training Program will ensure that trainees selected from a strong and diverse graduate community will provide sustained research contributions to benefit public health.

 描述（由申请人提供）：组织微环境培训计划（T32）项目摘要/摘要组织微环境（TiMe）的定量理解现在被认为是推进生物医学科学和医疗保健的关键，从再生医学到管理癌症负担。为此，三种技术方法的整合至关重要：（a）传感和成像，以测量生物化学和生物物理参数，（B）生物工程，以概括时间，（c）计算建模，以培养下一代生产性科学领导人。因此，我们提出了一个独特的教育平台，在这个平台上，博士前学生将整合使用三种技术方法在时间相关的研究中使用疾病和发展的生物背景。通过密集的指导和专注于专业发展的系统性活动，学员将成为下一代跨学科领导者，能够进行基础研究并实现转化进展。伊利诺伊大学厄巴纳-香槟分校拥有非常强大的学科课程，跨越课程知识弧的多元化教师，以及每个技术领域的适当设施和独特资源。该培训计划是由我们成功的研究生培训的强大历史，包括对多样性和残疾人的承诺，富有成效的合作文化，生物工程的新部门，以及强大的机构支持，明显地证明。39名教师，其中许多人目前正在合作的时间 研究，将担任教师导师。至少有8名受训人员将得到支助，每人最长可达两年。NIH支持的学员（4），由大学支持额外的学员（4，在第3年增加到5），将从校园内强大的申请人库中抽取。培训将包括四个核心部分-课程活动，以确保三个科技领域的深度和跨学科的适当广度;课外活动，以培养实用技能;专业发展，使学员成为研究领导者;以及职业发展，以确保学员对社会做出终身贡献。这些活动将以简化教育的方式进行结构化，使学生能够有效地专注于研究，并授予博士学位将包括一个特殊的称号（时间集中）。传统教育将进一步加强共同指导的研究与翻译机会的可能性，通过一个新的工程为基础的医学院。将在整个方案中对成果进行严格评估，以改进培训，指导行政决策并传播最佳做法。伊利诺伊州时间培训计划的愿景，专业知识和基础设施将确保从强大而多样化的研究生社区中选择的学员将提供持续的研究贡献，以造福公共卫生。