Tissue microenvironment (TiMe) training program

 描述(由申请人提供)：组织微环境培训计划(T32)项目摘要/摘要对组织微环境(时间)的定量了解现在被认为是促进生物医学科学和医疗保健的关键，范围从再生医学到管理癌症负担。为此，必须将三种技术方法结合起来：(A)测量生化和生物物理参数的传感和成像，(B)概括时间的生物工程，以及(C)培养下一代多产科学领袖的计算模型。因此，我们提出了一个独特的教育平台，博士前学生将利用疾病和发育的生物学背景，在与时间相关的研究中整合三种技术方法的使用。通过密集的指导和以专业发展为重点的系统活动，受训人员将成为能够进行基础研究和推动翻译进步的下一代跨学科领导者。伊利诺伊大学厄巴纳-香槟分校拥有非常强大的学科计划，在该计划的知识弧线上有不同的教员，在每个这些技术领域都有适当的设施和独特的资源。该培训计划明显得益于我们成功的研究生培训历史，包括对多样性和残疾人的承诺，富有成效的合作文化，新的生物工程系，以及强有力的机构支持。39名教员，其中许多人目前正在与《时代》杂志合作 研究，将担任教员导师。至少8名受训人员将得到最长两年的支持。NIH支持的实习生(4名)，加上大学对额外实习生的支持(4名，在第三年增加到5名)，将从校园内强大的申请者池中挑选出来。培训将包括四个核心部分-课程活动，以确保三个技术领域的深度和跨学科的适当广度；课外活动，以培养实用技能；专业发展，以增强学员成为研究领导者的能力；以及职业发展，以确保学员终身为社会做出贡献。这些活动的结构将以简化教育的方式进行，使学生能够有效地专注于研究，授予的博士学位将包括一个特殊的称号(集中时间)。传统教育将通过联合指导研究以及通过一个新的以工程为基础的医学院提供翻译机会的可能性来进一步加强。将在整个方案中严格评估结果，以改进培训、指导行政决策和传播最佳做法。伊利诺伊州时间培训计划的愿景、专业知识和基础设施将确保从强大和多样化的研究生社区中挑选出来的学员将为公众健康做出持续的研究贡献。

 DESCRIPTION (provided by applicant): Tissue Microenvironment Training Program (T32) Project Summary/Abstract A quantitative understanding of the tissue microenvironment (TiMe) is now recognized as critical for advancing biomedical science and healthcare, ranging from regenerative medicine to managing the burden of cancer. To this end, the integration of three technological approaches is essential: (a) sensing and imaging to measure biochemical and biophysical parameters, (b) bioengineering to recapitulate the TiMe, and (c) computational modeling to develop the next generation of productive scientific leaders. Accordingly, we propose a unique educational platform in which predoctoral students will integrate the use of the three technological approaches in TiMe-related studies using the biological contexts of disease and development. With intensive mentoring and systematic activities focused on professional development, trainees will become the next generation of interdisciplinary leaders capable of undertaking fundamental research and enabling translational advances. The University of Illinois at Urbana-Champaign has exceptionally strong disciplinary programs, diverse faculty spanning the intellectual arc of the program, and appropriate facilities and unique resources in each of these technological areas. The Training Program is distinctly advantaged by our strong history of successful graduate training, including a commitment to diversity and individuals with disabilities, a culture of productive collaboration, a new Department of Bioengineering, and strong institutional support. Thirty-nine faculty, many of whom are currently collaborating in TiMe research, will serve as faculty mentors. At least eight trainees will be supported for up to two years each. NIH-supported trainees (4), augmented by University support for additional trainees (4, ramping up to 5 in year 3), will be drawn from a strong applicant pool across campus. Training will include four core components-Curricular Activities to ensure depth in the three technological areas and apposite breadth across disciplines, Extracurricular Activities to develop pragmatic skills, Professional Development to empower trainees to become research leaders, and Career Development to ensure trainees make lifelong contributions to society. The activities will be structured in a manner to streamline education, allowing the students to focus efficiently on research, and the awarded doctoral degree will include a special designation (concentration in TiMe). Traditional education will further be enhanced by co- mentored research with possibilities of translational opportunities via a new engineering-based College of Medicine. Outcomes will be rigorously evaluated throughout the program to improve training, to guide administrative decision-making and to disseminate best practices. The vision, expertise, and infrastructure of the Illinois TiMe Training Program will ensure that trainees selected from a strong and diverse graduate community will provide sustained research contributions to benefit public health.