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iTAKL:Imaging Telemetry And Kinematic modeLing in youth football-High School

iTAKL：青少年足球中的成像遥测和运动学模型-高中

基本信息

批准号：
9981037
负责人：
Joseph A Maldjian
金额：
$ 62.33万
依托单位：
WAKE FOREST UNIVERSITY HEALTH SCIENCES
依托单位国家：
美国
项目类别：
财政年份：
2016
资助国家：
美国
起止时间：
2016-07-01 至 2022-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9981037
关键词：
18 year old Adolescence Adolescent Adverse effects Affect Age Anisotropy Area Athletic Atlases Attention Base of the Brain Behavior assessment Biomechanics Biometry Brain Brain Concussion Brain Injuries Brain imaging Childhood Cognitive Collaborations Collection Computer Models Control Groups Craniocerebral Trauma Data Development Diffuse Diffusion Magnetic Resonance Imaging Elements Exposure to Freedom Functional Magnetic Resonance Imaging Funding Growth and Development function Head Health Sciences Image Incidence Injury Investments Linear Regressions Magnetic Resonance Imaging Magnetoencephalography Manufactured football Measures Modeling Monitor Motion Neurocognitive Neuropsychology Outcome Participant Perfusion Predisposition Public Health Recording of previous events Regression Analysis Research Personnel Rest Risk Rotation Scanning Seasons Slow-Wave Sleep Spin Labels Sports Structure System Techniques Telemetry Time Translating Traumatic Brain Injury United States National Institutes of Health Universities Work Youth base clinical Diagnosis clinical epidemiology cognitive change cognitive function cognitive testing college data acquisition data modeling design executive function experience forest functional outcomes gray matter head impact high risk high school instrument interest kinematics mild traumatic brain injury multimodality neuroimaging neuroinformatics pediatric traumatic brain injury prospective public health relevance recruit research clinical testing response white matter

项目摘要

DESCRIPTION (provided by applicant): Football head injuries involve significant forces and can result in mild to severe traumatic brain injuries. While this has received increasing attention at the professional and collegiate levels, there is less data available for the millions of participants in high school leagues (14-18 years old) during this time of rapid brain development. The purpose of this study is to relate information about cumulative head impact exposure over a season of high school football with neurocognitive and neuroimaging data to determine the effects of sub-concussive impacts on the brain. All elements of this study focus on the objective to increase understanding of pediatric mild Traumatic Brain Injury (mTBI) and prospectively collect biomechanical, imaging, functional, and computational modeling data on a scale never before attempted in adolescents involved in contact sports. This project integrates neuroinformatics work and the computational modeling techniques developed by Drs. Whitlow, Maldjian and Stitzel at Wake Forest University Health Sciences.