MULTIDISCIPLINARY TRAINING IN PULMONARY RESEARCH

摘要 这一机构国家研究服务奖旨在培养具有研究能力的调查人员- 以解决肺部疾病的基本、翻译和临床问题为导向的职业。的结构 该计划的前提是，培训需要1)多学科方法，2)近距离 学生/博士后和指导团队之间的关系，以及3)具有广度和 精通基础科学、翻译科学和临床科学。该肺科项目的培训跨越多个学科 包括细胞和分子生物学、免疫学、微生物学、毒理学、生物化学、肺部和危重 护理医学、传染病和新生儿科。主要研究主题包括：肺免疫学， 炎症和感染；肺纤维化和重塑；烟草和生物质烟雾与慢性 阻塞性肺病；以及空气污染对健康的影响。4名博士后和4名博士后 受训人员每年都会得到资助。对肺部研究感兴趣的博士后学生将被录取 通过生物医学科学研究生教育(GEBS)计划的培训 他们的资格考试。博士前实习生将获得长达3年的支持。博士后博士 参与肺部相关研究的受训人员也是培训对象，并由以下机构确定和招募 这个项目的成员。MD/DO候选人来自成人肺和肺的培训计划 重症监护医学、过敏/免疫学/风湿病学、新生儿学和传染病。只有 最好的候选人将根据潜在的成功和对肺部疾病的认真承诺来考虑 以研究为导向的职业。在本周期的培训赠款期间，我们建立并成功地 为一个新的研究轨道招募了两名MD实习生。这条路线需要4年的子专业培训， 在最后两年对这笔赠款进行的研究培训和支持，以及对 在培训结束前提交出版物和研究补助金。关于研究的直接研究体验 导师是主要的培训机制，辅以授课课程、研讨会、会议、 杂志俱乐部，以及研究伦理、人体和动物实验以及拨款写作方面的指导。全 学员可以在职业发展路径、拨款撰写、关键课程方面获得新的机构范围的计划 思考、体验式学习等等。项目实习生还将制定研究方案和计划 在他们的指导团队的监督下。该培训计划将有助于满足以下方面的多样化需求 学术界、政府和工业界肺部生物学和疾病的科学研究人员。研究和 这些受训者的扩展培训将增强我们对呼吸系统如何应对 伤害和环境挑战，并将通过开发新的和改进的途径来改善公共健康 用于预防和治疗肺部疾病。

Abstract This Institutional National Research Service Award is designed to develop skilled investigators with research- oriented careers directed at solving basic, translational and clinical problems in lung disease. The structure of the program is based on the premise that training requires 1) a multidisciplinary approach, 2) a close relationship between the student/postdoc and mentoring team, and 3) a training environment with breadth and depth in basic, translational and clinical sciences. Training in this Pulmonary program spans disciplines that include cell and molecular biology, immunology, microbiology, toxicology, biochemistry, pulmonary and critical care medicine, infectious diseases and neonatology. Major research themes include: lung immunology, inflammation and infection; pulmonary fibrosis and remodeling; tobacco and biomass smoke and chronic obstructive pulmonary disease; and the health effects of air pollution. Four predoctoral and 4 postdoctoral trainees will be supported each year. Predoctoral students interested in lung research will be accepted for training through the Graduate Education in Biomedical Sciences (GEBS) programs, after they have passed their qualifying examinations. Predoctoral trainees will be supported for up to 3 years. Postdoctoral PhD trainees involved in lung-related research are also candidates for training, and are identified and recruited by members of this program. The MD/DO Candidates come from training programs in adult Pulmonary and Critical Care Medicine, Allergy/Immunology/Rheumatology, Neonatology, and Infectious Diseases. Only the top candidates will be considered based on potential success in and serious commitment to a pulmonary research-oriented career. During the current cycle of the training grant, we established and successfully recruited two MD trainees for a new research track. This track requires 4 years of subspecialty training with research training and support on this grant occurring in the final 2 years, and specific expectations of publications and research grant submission by the end of training. A direct research experience with research mentors forms the primary mechanism for training, supplemented by didactic courses, seminars, conferences, journal clubs, and instruction in research ethics, human and animal experimentation, and grant writing. All trainees have access to new Institution-wide programs in career development paths, grant writing, critical thinking, experiential learning and more. Program trainees will also develop research protocols and plans under the supervision of their mentoring team. This training program will help to meet the diverse need for scientific investigators in lung biology and disease in Academia, Government, and Industry. Research and expanded training by these trainees will enhance our understanding of how the respiratory system responds to injury and environmental challenges, and will improve public health by developing new and improved avenues for the prevention and treatment of lung disease.