Core-003

翻译奋进核心提供了一支翻译劳动力的发展和提供奖励 在OCTRI内加强研究发展的计划。 OCTRI翻译劳动力计划包括非常成功的研究、教育和职业 在过去的15年里制定了发展计划。实施了研究培训计划 具体到职业发展阶段：本科生；研究生博士、医学博士、DMD和药学博士 学生；博士后和临床研究员；以及早期教员。人类调查计划提供 临床和转化性研究能力方面的培训是所有计划的基础。具体培训 对于学生，包括医生-科学家轨道，临床和转化性研究的助理，以及 为研究生开设的对开课程。OCTRI奖学金计划提供更好的指导和 支持被指导的职业发展奖获得者，以增加实现研究独立的几率。 在下一个赠款期间，我们将把这些成功的培训单元分发给CTSA财团， 特别是生物统计学和生物信息学。我们将通过创建一项研究来加强对早期教师的培训 将缺乏经验的临床医生或科学家与有经验的研究导师配对的开发团队 在团队的协助下设计、提交资金并实施研究方案；同一团队 将致力于解决早期研究人员的实施障碍。最后，我们将提高这一比例 临床研究专业人员通过加强和专注于实现特定研究能力 通过一系列综合培训课程对研究人员进行培训。 OCTRI试点和临床研究计划为研究人员提供资金和资源，以推动 他们的研究进入了下一阶段。Pilot Awards计划也是设计和设计的“活实验室” 传播影响临床治疗效率和疗效的研究、过程和评估方法 和翻译研究。该计划包括四个关键的资助机制：OCTRI催化剂奖， OCTRI社区研究联盟奖、战略投资和生物医学创新 程序。在下一个授权期内，我们将扩大与OCTRI合作伙伴的竞争准入。我们将添加一个 为早期职业研究人员设立的额外机制--独立之路奖。这一奖项将 资助可能会影响他们职业发展轨迹的研究。我们将随机地对这个模型进行实验测试 分配受赠者接受或不接受密集劳动力发展和团队科学的一揽子计划 干预措施。此外，我们将集中我们已经严格和透明的审查程序，形成一个 所有试点奖项的单一常设审查委员会，将纳入外部和跨CTSA审查人员。 OCTRI奖方案将继续改进其成功的评价方法，传播结果 在CTSA网络和评估界广泛传播。

The Translational Endeavor core provides for developing a translational workforce and for providing an awards program to enhance research development within OCTRI. The OCTRI Translational Workforce program includes the highly successful research education and career development programs developed over the past 15 years. Research training programs have been implemented specific to the career development phase: undergraduate students; graduate PhD, MD, DMD, and PharmD students; postdoctoral and clinical fellows; and early faculty. The Human Investigations Program provides training in the competencies of clinical and translational research and underlies all programs. Specific training for students includes the physician-scientist track, a clerkship in clinical and translational research, and the FOLIO program for graduate students. The OCTRI Scholar program provides enhanced mentorship and support to mentored career development awardees to increase the odds of achieving research independence. During the next grant period, we will disseminate these successful training modules to the CTSA consortium, particularly biostatistics and bioinformatics. We will enhance our training for early faculty by creating a research development team that pairs an inexperienced clinician or scientist with an experienced research mentor to design, submit for funding, and implement a research proposal with the assistance of the team; this same team will work to problem solve implementation barriers for early researchers. Finally, we will increase the proportion of clinical research professionals who achieve specific research competencies by strengthening and focusing research staff training through an integrated series of training sessions. The OCTRI Pilots and Clinical Studies program provides investigators with funding and resources to advance their research to the next stage. The Pilot Awards Program also serves as a “living lab” for the design and dissemination of research, process, and evaluation methods that impact the efficiency and efficacy of clinical and translational research. The program comprises four key funding mechanisms: OCTRI Catalyst Awards, OCTRI Community Research Coalition Awards, Strategic Investments, and the Biomedical Innovation Program. Over the next grant period we will expand competitive access to our OCTRI partners. We will add an additional mechanism, the Pathways to Independence Award, for early career researchers. This award will fund research likely to impact their career trajectories. We will test this model experimentally, randomly assigning grantees to receive or not receive a package of intensive workforce development and team science interventions. In addition, we will centralize our already rigorous and transparent review process, forming a single standing review committee for all pilot awards that will incorporate external and cross-CTSA reviewers. The OCTRI Awards Program will continue to refine its successful evaluation approach, disseminating findings widely across the CTSA network and the evaluation community.