Core-003

翻译奋进核心旨在培养翻译人才并提供奖励 该计划旨在加强OCTRI内部的研究开发。 OCTRI翻译劳动力计划包括非常成功的研究教育和职业生涯 过去15年来制定的发展计划。已实施研究培训方案 具体到职业发展阶段：本科生;研究生博士，医学博士，DMD和药学博士 学生;博士后和临床研究员;和早期教师。人类研究计划提供 临床和转化研究能力的培训，并成为所有计划的基础。具体培训 为学生提供的课程包括医生-科学家课程，临床和转化研究的实习，以及 FOLIO计划的研究生。OCTRI奖学金计划提供增强的指导， 支持接受指导的职业发展获奖者，以增加实现研究独立的可能性。 在下一个资助期内，我们将把这些成功的培训单元分发给CTSA财团， 特别是生物统计学和生物信息学。我们将通过创建一个研究， 开发团队，将经验不足的临床医生或科学家与经验丰富的研究导师配对， 设计，提交资金，并在团队的协助下实施研究提案;同一团队 将致力于解决早期研究人员的实施障碍。最后，我们将提高比例 临床研究专业人员谁实现具体的研究能力，通过加强和重点 通过一系列综合培训课程对研究人员进行培训。 OCTRI试点和临床研究计划为研究人员提供资金和资源， 他们的研究进入下一阶段试点奖励计划也作为一个“生活实验室”的设计和 传播影响临床效率和疗效的研究、过程和评估方法 和翻译研究。该计划包括四个关键的资助机制：OCTRI催化剂奖， OCTRI社区研究联盟奖，战略投资和生物医学创新 程序.在下一个资助期内，我们将扩大我们的OCTRI合作伙伴的竞争机会。我们将添加一个 为早期职业研究人员设立了一个额外的机制，即独立之路奖。这个奖项将 资助可能影响其职业轨迹的研究。我们将通过实验随机地测试这个模型 分配受助人接受或不接受一套密集的劳动力发展和团队科学 干预措施。此外，我们将把本已严格和透明的审查程序集中起来，形成一个 针对所有试点奖励的单一常设审查委员会，将纳入外部和跨CTSA审查人员。 OCTRI奖励计划将继续完善其成功的评估方法， 在CTSA网络和评价界广泛传播。

The Translational Endeavor core provides for developing a translational workforce and for providing an awards program to enhance research development within OCTRI. The OCTRI Translational Workforce program includes the highly successful research education and career development programs developed over the past 15 years. Research training programs have been implemented specific to the career development phase: undergraduate students; graduate PhD, MD, DMD, and PharmD students; postdoctoral and clinical fellows; and early faculty. The Human Investigations Program provides training in the competencies of clinical and translational research and underlies all programs. Specific training for students includes the physician-scientist track, a clerkship in clinical and translational research, and the FOLIO program for graduate students. The OCTRI Scholar program provides enhanced mentorship and support to mentored career development awardees to increase the odds of achieving research independence. During the next grant period, we will disseminate these successful training modules to the CTSA consortium, particularly biostatistics and bioinformatics. We will enhance our training for early faculty by creating a research development team that pairs an inexperienced clinician or scientist with an experienced research mentor to design, submit for funding, and implement a research proposal with the assistance of the team; this same team will work to problem solve implementation barriers for early researchers. Finally, we will increase the proportion of clinical research professionals who achieve specific research competencies by strengthening and focusing research staff training through an integrated series of training sessions. The OCTRI Pilots and Clinical Studies program provides investigators with funding and resources to advance their research to the next stage. The Pilot Awards Program also serves as a “living lab” for the design and dissemination of research, process, and evaluation methods that impact the efficiency and efficacy of clinical and translational research. The program comprises four key funding mechanisms: OCTRI Catalyst Awards, OCTRI Community Research Coalition Awards, Strategic Investments, and the Biomedical Innovation Program. Over the next grant period we will expand competitive access to our OCTRI partners. We will add an additional mechanism, the Pathways to Independence Award, for early career researchers. This award will fund research likely to impact their career trajectories. We will test this model experimentally, randomly assigning grantees to receive or not receive a package of intensive workforce development and team science interventions. In addition, we will centralize our already rigorous and transparent review process, forming a single standing review committee for all pilot awards that will incorporate external and cross-CTSA reviewers. The OCTRI Awards Program will continue to refine its successful evaluation approach, disseminating findings widely across the CTSA network and the evaluation community.