Core-005

OHSU在儿童健康、老年人口、终身疾病等方面拥有强大的研究组合，以及 服务不足的农村人口。然而，在对这些方面的协调支持方面存在着重大差距 损害这些努力的最佳性能和扩展的重要计划。新的OCTRI 整合特殊人口单位将加强儿童健康、老年人口、疾病等方面的研究 对当前需求、发展和未得到充分服务的农村人口进行关键分析 确定满足这些需求的可行目标，落实最高优先目标，以及评价和 传播最有效的进程。计划的活动包括区域会议和务虚会 与调查人员和其他利益攸关方合作，开发工具包和其他教育模块，加强 信息学工具，以及为每个程序量身定做的其他技术。互联网服务供应商将与 CTSA网络采用其他CTSA站点开发的有效技术，并分享当地经过验证的 经过仔细评估后的技术。这些努力将加强对这些地区与健康有关的问题的了解 改善干预措施，以优化他们的健康和福祉。 OCTRI临床和翻译研究中心(CTRC)极大地扩展和增强了 在OHSU进行临床研究，在过去五年中取得了前所未有的增长。反恐委员会还 作为OHSU临床研究职业发展的主要场所。然而，CTRC上的压力源 业务和财务结构需要新的筹资模式和更高的业务效率。 这些成就和挑战为八达通社参与者和 未来五年的临床交互(PCI)研究能力。CTRC将以科学的方式催化 严谨、合乎道德、可行和高效的以患者为中心的研究，重点是强化研究 OHSU研究人员在高优先领域的表型和早期临床试验。这些努力将 增进对多种人类疾病的认识，为疾病特异性治疗奠定基础 以增进人类健康。反恐委员会还将继续利用和加强OCTRI教育 通过利用CTRC作为学生、研究人员和研究人员的指导性“实验室”来计划 坚持以病人为中心的研究。最后，反恐委员会将完成向新的业务部门的过渡。 将模型作为大学共享资源(USR)，结合持续质量改进以确保 建立了可持续和高效的业务和财务程序，以便以最佳方式支持公共部门改革 在俄亥俄州立大学和该地区进行研究。

OHSU has a robust research portfolio in child health, older populations, diseases across the lifespan, and underserved rural populations. However, there are significant gaps in coordinated support for these important programs that impair optimal performance and expansion of these efforts. The new OCTRI Integrating Special Populations unit (ISP) will enhance research in child health, older populations, diseases across the lifespan, and underserved rural populations with a critical analysis of current needs, development of feasible goals to address these needs, implementation of the highest priority goals, and evaluation and dissemination of the most effective processes. Planned activities include regional conferences and retreats with investigators and other stakeholders, development of toolkits and other educational modules, enhanced informatics tools, and other techniques tailored to each program. The ISP will coordinate closely with the CTSA network to adopt effective techniques developed at other CTSA sites, and to share local proven techniques after careful evaluation. These efforts will enhance knowledge of health-related issues in these special populations, leading to improved interventions to optimize their health and well-being. The OCTRI Clinical and Translational Research Center (CTRC) has greatly expanded and enhanced the conduct of clinical research at OHSU, with unprecedented growth over the past five years. The CTRC also serves as a major site for career development in clinical research at OHSU. However, stressors on CTRC operational and financial structures require a new funding model and increased operational efficiencies. These accomplishments and challenges set the stage for continued evolution of OCTRI’s Participant and Clinical Interactions (PCI) research capacity for the next five years. The CTRC will catalyze scientifically rigorous, ethical, feasible, and efficient patient-oriented research studies, with an emphasis on intensive phenotyping and early phase clinical trials in high priority areas for OHSU investigators. These efforts will advance knowledge of numerous human diseases and lay the foundations for disease-specific therapeutics to enhance human health. The CTRC will also continue to leverage and enhance the OCTRI Educational Program by utilizing the CTRC as the mentored “laboratory” for students, investigators, and study staff pursuing patient- oriented research. Finally, the CTRC will complete its transition to a new operational model as a University Shared Resource (USR), incorporating continuous quality improvement to ensure that sustainable and efficient operational and financial processes are in place to optimally support PCI research at OHSU and the region.