RNA Sequencing and Data Analysis Core

RNA测序和数据分析核心摘要： 核糖核酸测序和数据分析核心的目标是为核糖核酸提供集中服务 该计划的测序和生物信息学需求。这一核心的好处包括资源和专业知识 为了进行RNA测序实验，获得最新的设备、试剂盒和概念，以及 用于测序和综合组学分析的尖端方法和工具。 该团队在小RNA和mRNA(长)RNA测序和分析方面特别熟练， 强调这些数据与其他组学数据集的集成。Core提供的许多服务 由范德比尔特大学医学中心(VUMC)的成员开发和优化 领导团队，包括用于小RNA测序的尖端协议和分析管道 胞外RNA。核心人员在生物技术、生物信息学和 生物统计学。核心将1)执行高通量的小RNA和总RNA测序以及其他 测序实验；2)提供多组学数据分析和解释；3)开发新的一体化 方法寻找结直肠癌细胞外RNA生物发生和功能的关键调控因子。

RNA Sequencing and Data Analysis Core Summary: The goal of the RNA Sequencing and Data Analysis Core is to provide a centralized service for RNA sequencing and bioinformatics needs of the program. The benefits of this core include resources and expertise to perform RNA sequencing experiments, access to the most up-to-date equipment, kits and concepts, and cutting edge methods and tools for sequencing and integrative omics analyses. This team is particularly skilled in small RNA and mRNA (long) RNA sequencing and analyses, with emphasis on integration of these data with other -omics datasets. Many of the services provided by the Core have been developed and optimized at Vanderbilt University Medical Center (VUMC) by members of the leadership team, including cutting-edge protocols and analysis pipelines for small RNA sequencing of extracellular RNAs. The Core personnel have complementary expertise in biotechnology, bioinformatics, and biostatistics. The Core will 1) perform high throughput small RNA and total RNA sequencing, as well as other sequencing experiments; 2) provide multi-omics data analysis and interpretation; 3) develop novel integrative methods to discover key regulators in extracellular RNA biogenesis and function in colorectal cancer.