Biostatistics

生物统计学

• 批准号: 8764763
• 负责人: Yu Shyr
• 金额: $ 17.6万
• 依托单位: VANDERBILT UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-09-01 至 2018-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8764763
• 关键词: Bioinformatics; Biometry; Biostatistics Core; Clinical Research; Collaborations; Conceptions; Data; Data Analyses; Data Quality; Databases; Development; Ensure; Experimental Designs; Human Resources; Image; Informatics; Instruction; Laboratory Animals; Longevity; Manuscripts; Methods; Participant; Pathology; Quality Control; Reporting; Research Design; Research Personnel; Research Project Grants; Sample Size; Services; Tissues; Work; Writing; anticancer research; malignant breast neoplasm; member; research and development; sound

The purpose of the Biostatistics Core is to provide professional expertise in biostatistics and bioinformatics for all Breast Cancer SPORE projects, investigators, and participants. Functions provided by this core include development of experimental designs, power analysis, and sample size estimation; data quality control statistical/bioinformatic analysis and interpretation of findings; and collaboration on presentation of results. To achieve these functions, the core director and core members are constantly available to investigators, and are in regular contact with project and core leaders. The primary objectives ofthe Biostatistics Core are: 1. To provide study design and review all laboratory, animal, and clinical studies including feasibility assessment, power analysis, and sample size estimation 2. To collaborate in project data analysis, interpretation of results, and the writing of final study reports and manuscripts 3. To work with the Pathology & Tissue Informatics Core and Imaging Core in the development of research project databases, to maintain data quality control and to ensure timely data capture 4. To develop and evaluate statistical/bioinformatic methods for experimental design and data analysis Biostatistics Core support is required in all Breast Cancer SPORE studies. Core personnel have worked and will continue to work closely with project leaders to ensure the core provides state-of-the-art statistical/bioinformatic support. RELEVANCE (See instructions): The relevance of the Biostatistics Core lies in our provision of services essential for the conduct of high-quality collaborative breast cancer research; sound statistical/bioinformatics inputs are critical throughout the lifespan of a research project, from conception to completion.

生物统计核心的目的是提供生物统计和生物信息学方面的专业知识 所有乳腺癌孢子项目、调查人员和参与者。该内核提供的功能包括 开展实验设计、能量分析和样本量估计；数据质量控制 对调查结果进行统计/生物信息学分析和解释；以及在提出结果方面进行合作。至 为了实现这些职能，核心主任和核心成员随时可供调查人员使用，并 与项目和核心领导保持定期联系。 生物统计核心的主要目标是： 1.提供研究设计并审查所有实验室、动物和临床研究，包括可行性 评估、能量分析和样本量估计 2.在项目数据分析、结果解释和撰写最终研究报告方面进行合作 和手稿 3.与病理学和组织信息学核心和成像核心合作开发 研究项目数据库，以维持数据质量控制并确保及时获取数据 4.开发和评估用于实验设计和数据分析的统计/生物信息学方法 生物统计学在所有乳腺癌孢子研究中都需要核心支持。核心人员已经工作并 将继续与项目负责人密切合作，以确保核心提供最先进的 统计/生物信息支持。 相关性(请参阅说明)： 生物统计核心的相关性在于我们提供的服务对于开展高质量的 协作性乳腺癌研究；健全的统计/生物信息学输入在整个生命周期中至关重要 一个研究项目，从构思到完成。