From the Scanner to the Clinic: Patient Oriented Research and Mentorship

从扫描仪到诊所：以患者为中心的研究和指导

• 批准号: 10668383
• 负责人: Diana M Martinez
• 金额: $ 12.12万
• 依托单位: NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-08-15 至 2025-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10668383
• 关键词: Accident and Emergency department; Alcohols; Anesthetics; Anterior; Auditory area; Award; Breast Cancer Patient; Cannabidiol; Cannabinoids; Cannabis; Chronic; Clinic; Clinical; Clinical Investigator; Clinical Research; Clinical Trials; Crossover Design; Dedications; Department of Defense; Development; Dose; Education; Educational Intervention; Effectiveness; Faculty; Family; Foundations; Frequencies; Funding; Future; Glutamates; Goals; Image; Inpatients; Intervention; Investigation; Ketamine; Knowledge; Laboratories; Magnetic Resonance Imaging; Measures; Medial; Medical Students; Medication Systems; Mentors; Mentorship; Methadone; Midcareer Investigator Award in Patient-Oriented Research; N-Methylaspartate; National Institute on Alcohol Abuse and Alcoholism; Neurosciences Research; Neurotransmitters; Opioid; Oral; Outcome Measure; Overdose; Pain; Paresthesia; Participant; Patients; Peripheral Nervous System Diseases; Pharmaceutical Preparations; Physicians; Placebos; Positioning Attribute; Positron-Emission Tomography; Postdoctoral Fellow; Prefrontal Cortex; Provider; Psychiatrist; Psychiatry; Questionnaires; Randomized; Research; Research Personnel; Role; Self Administration; Sensory; Severities; Substance Use Disorder; Support System; Tactile; Testing; Time; Tinnitus; Training; Transcranial magnetic stimulation; Universities; Work; active method; addiction; alcohol use disorder; allodynia; antagonist; brain volume; capsule; career; chronic pain; cingulate cortex; design; experience; gamma-Aminobutyric Acid; hearing impairment; improved; methadone treatment; non-cancer chronic pain; patient oriented research; pre-doctoral; primary outcome; programs; recruit; reinforcer; research study; skills; taxane; volunteer

Enter the text here that is the new abstract information for your application. This section must be no longer than 30 lines of text. The overall goal of this application is to allow the investigator (Diana Martinez, MD) to engage in new directions in research while providing mentorship to trainees pursuing careers in substance use disorders (SUD) research. The new directions in research include interventional psychiatry for SUD, as follows: 1) a clinical trial of transcranial magnetic stimulation (TMS) for cocaine use disorder; 2) a human laboratory self-administration trial of alcohol use disorder using TMS; and 3) an investigation of ketamine combined with mindfulness (delivered via a free mobile phone app) to address smoking cessation. The advantage of these types of procedures is that they could be implemented in a clinical setting should they have clinical efficacy. These new directions in research are combined with mentorship. Dr. Martinez is now the co-director of our institution’s T32 program (Translational Clinical Research Fellowship on Substance Use Disorders). In this capacity, Dr. Martinez is involved overseeing the daily management of the program. These responsibilities include matching fellows with mentors; assisting fellows with protocol submissions; reviewing and revising applications for pilot awards; reviewing and critiquing fellows’ grant submissions and ensuring that fellows meet milestones. Dr. Martinez is director of our T32’s Early Action pipeline program, which serves to increase interest among medical students in research careers dedicated to developing treatments for SUD.

在此输入文本，它是您的应用程序的新摘要信息。此部分不得超过30行文本。 该应用程序的总体目标是允许研究人员(医学博士戴安娜·马丁内斯)从事新的研究方向，同时为寻求物质使用障碍(SUD)研究职业的受训者提供指导。新的研究方向包括SUD的介入精神病学，如下：1)经颅磁刺激(TMS)治疗可卡因使用障碍的临床试验；2)使用TMS进行酒精使用障碍的人体实验室自我管理试验；以及3)氯胺酮与正念相结合的调查(通过免费手机应用程序提供)以解决戒烟问题。这些类型的程序的优点是，它们可能是 如果它们具有临床疗效，则在临床环境中实施。这些研究的新方向与导师的指导相结合。马丁内斯博士现在是我们机构T32项目(物质使用障碍翻译临床研究奖学金)的联席主任。在这个职位上，马丁内斯博士负责监督该项目的日常管理。这些职责包括为研究员与导师配对；协助研究员提交方案；审查和修订试点奖项的申请；审查和批评研究员的赠款申请，并确保研究员达到里程碑。马丁内斯博士是我们的T32‘S早期行动管道项目的负责人，该项目旨在提高医学生对致力于开发SUD治疗方法的研究职业的兴趣。

项目成果

Addiction as a brain disease revised: why it still matters, and the need for consilience.

• DOI: 10.1038/s41386-020-00950-y
• 发表时间: 2021-09
• 期刊: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology
• 作者: Heilig M;MacKillop J;Martinez D;Rehm J;Leggio L;Vanderschuren LJMJ
• 通讯作者: Vanderschuren LJMJ

Racial differences in COVID-19 severity associated with history of substance use disorders and overdose: Findings from multi-site electronic health records in New York City.

• DOI: 10.1016/j.ypmed.2023.107533
• 发表时间: 2023-07
• 期刊: PREVENTIVE MEDICINE
• 影响因子: 5.1
• 作者: Allen, Bennett;Basaraba, Cale;Corbeil, Thomas;Rivera, Bianca D.;Levin, Frances R.;Martinez, Diana M.;Schultebraucks, Katharina;Henry, Brandy F.;Pincus, Harold A.;Arout, Caroline;Krawczyk, Noa
• 通讯作者: Krawczyk, Noa

The impact of preexisting psychiatric disorders and antidepressant use on COVID-19 related outcomes: a multicenter study.

• DOI: 10.1038/s41380-023-02049-4
• 发表时间: 2023-06
• 期刊: MOLECULAR PSYCHIATRY
• 影响因子: 11
• 作者: Schultebraucks, Katharina;Blekic, Wivine;Basaraba, Cale;Corbeil, Tom;Khan, Zain;Henry, Brandy F. F.;Krawczyk, Noa;Rivera, Bianca D. D.;Allen, Bennett;Arout, Caroline;Pincus, Harold Alan;Martinez, Diana M. M.;Levin, Frances R. R.
• 通讯作者: Levin, Frances R. R.