ACTIVITY 4: BIOSTATISTICS AND COMPUTER CORE SUPPORT SERVICES

这个子项目是许多利用 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 这项活动的总体目标是扩大和加强生物统计数据管理设施（BDMF）和计算机网络支持设施（CNSF）的能力，以便在生物统计分析、计算机建模、基于网络的数据输入、数据库开发和管理、数据存储、联网、连接、视频会议和培训，以满足马诺阿夏威夷大学快速增长的生物医学研究人员的需要。CNSF最初是从1992年开始与RCMI基金一起开发的。 BDMF成立于2004年，由RCMI提供资金。在2006-2011年供资周期，联邦发展基金将重点致力于以下方面：（1）发展结构方程建模方面的专门知识，重点是多维神经元成像数据领域;（2）开发一个基于网络的系统，用于将数据输入适合存档和统计提取的分级数据管理系统; 3）继续开发通用软件，以计算多变量统计程序的功效/样本量;以及4）扩展用于分析基因-环境相互作用的软件工具。 CNSF正在规划其RCMI在以下领域的工作：⑴扩大数据管理和数据库服务; ⑵扩大网络和通信服务; ⑶扩大桌面和演示服务。 这两个设施在实现其目标方面取得了重大进展，并将两个设施结合起来，为90多名生物医学研究人员和众多其他教职员工和学生提供服务。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The overall goal of this activity is to expand and enhance the capabilities of both the Biostatistics Data Management Facility (BDMF) and the Computer Network Support Facility (CNSF) to deliver state-of-the-art services in biostatistical analysis, computer modeling, web-based data entry, database development and management, data storage, networking, connectivity, video conferencing and training to meet the needs of the fast-growing cadre of biomedical researchers at the University of Hawaii at Manoa. The CNSF was originally developed with RCMI funds beginning in 1992. The BDMF was established in 2004 with RCMI funds. In the 2006-2011 funding cycle the BDMF is focusing its efforts on the following: 1) developing expertise in structural-equation modeling with emphasis in the area of multidimensional neuron-imaging data; 2) developing a web-based system for data entry into a hierarchical data-management system suitable for archival and statistical extraction; 3) continuing to develop generalized software to calculation power/sample size for multivariate statistical procedures; and 4) expanding the software tools for the analysis of gene-environment interactions. The CNSF is planning its RCMI efforts in the following areas: 1) expanding data management and database services; 2) expanding network and communication services; and 3) expanding desktop and presentation services. Major progress has been made in both facilities towards their aims and combined the two facilities provide services to over 90 biomedical investigators and numerous other faculty, staff and students.