ACTIVITY 4: BIOSTATISTICS AND COMPUTER CORE SUPPORT SERVICES

该子项目是利用 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得主要资金， 因此可以在其他CRISP条目中表示。列出的机构是 中心，不一定是研究者的机构。 这项活动的总体目标是扩大和加强由Efird博士领导的生物统计数据管理设施（BDMF）和由Jones博士领导的计算机网络支持设施（CNSF）的能力。总体目标是在生物统计分析、计算机建模、基于网络的数据输入、数据库开发和管理、数据存储、联网、连通性、视频会议和培训方面提供最先进的服务，以满足位于马诺阿的夏威夷大学快速增长的生物医学研究人员队伍的需求。CNSF最初是从1992年开始与RCMI基金一起开发的。BDMF成立于2004年，由RCMI提供资金。在2006-2011年供资周期，联邦发展基金将重点致力于以下方面：（1）发展结构方程建模方面的专门知识，重点是多维神经元成像数据领域;（2）开发一个基于网络的系统，用于将数据输入适合存档和统计提取的分级数据管理系统; 3）继续开发通用软件，以计算多变量统计程序的功效/样本量;以及4）扩展用于分析基因-环境相互作用的软件工具。CNSF将其RCMI的工作重点放在以下领域：⑴扩大数据管理和数据库服务; ⑵扩大网络和通信服务; ⑶扩大桌面和演示服务。这些目标指导着每个设施的主要工作，并为它们的合作和交叉提供了蓝图。这两个设施结合起来，为90多名生物医学研究人员和许多其他教职员工和学生提供服务。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The overall goal of this activity is to expand and enhance the capabilities of both the Biostatistics Data Management Facility (BDMF), directed by Dr. Efird, and the Computer Network Support Facility (CNSF), directed by Dr. Jones. The overall goal is to deliver state-of-the-art services in biostatistical analysis, computer modeling, web-based data entry, database development and management, data storage, networking, connectivity, video conferencing and training to meet the needs of the fast-growing cadre of biomedical researchers at the University of Hawaii at Manoa. The CNSF was originally developed with RCMI funds beginning in 1992. The BDMF was established in 2004 with RCMI funds. In the 2006-2011 funding cycle the BDMF is focusing its efforts on the following: 1) developing expertise in structural-equation modeling with emphasis in the area of multidimensional neuron-imaging data; 2) developing a web-based system for data entry into a hierarchical data-management system suitable for archival and statistical extraction; 3) continuing to develop generalized software to calculation power/sample size for multivariate statistical procedures; and 4) expanding the software tools for the analysis of gene-environment interactions. The CNSF is focusing its RCMI efforts in the following areas: 1) expanding data management and database services; 2) expanding network and communication services; and 3) expanding desktop and presentation services. These aims guide the major work of each facility and they provide the blueprint for their collaboration and intersection. Combined, the two facilities provide services to over 90 biomedical investigators and numerous other faculty, staff and students.