HANGOVER, CONGENERS, SLEEP, AND OCCUPATIONAL PERFORMANCE

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 其目的是调查有或没有宿醉症状的大量饮酒的后遗症。主要目的是检验关于大量饮酒后遗症的几个假说。关于重度饮酒对第二天表现的影响的假设包括酒精的直接生理影响、酒精戒断影响和非酒精影响，如同系物或酒精问题家族史。我们将检验以下假设：(1)相对于安慰剂，大量饮酒会降低第二天的表现，这种关系将完全或部分通过睡眠质量来调节；(2)高同类酒精饮料对表现的影响将比低同类饮料更大，这种关系将由宿醉症状的严重程度来调节。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The objective is to investigate residual effect of heavy drinking, with or without hangover symptoms. The primary aim is to test several hypotheses about residual effect of heavy drinking. Hypotheses about how heavy drinking effect next- day performance include direct physiological effects of alcohol, alcohol withdrawal effects, and non-ethanol effects, such as congeners or family history of alcohol problems. We will test the following hypotheses: (1) relative to placebo, heavy drinking will degrade next-day performance, and this relationship will be mediated in full or in part by quality of sleep; (2) a high congener alcoholic beverage will affect performance to a greater degree than a low congener beverage and this relationship will be mediated by severity of hangover symptoms.