PG SYNTHESIS INHIBITION ON VASODILATOR CAPACITY W REACTIVE HYPEREMIA & HYPOXIA

反应性高血症时 PG 合成对血管舒张能力的抑制

• 批准号: 7625795
• 负责人: URS A LEUENBERGER
• 金额: $ 0.69万
• 依托单位: PENNSYLVANIA STATE UNIV HERSHEY MED CTR
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-04-01 至 2008-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7625795
• 关键词: Blood flow; Computer Retrieval of Information on Scientific Projects Database; Funding; Grant; Hypoxia; Institution; Metabolic; Obstructive Sleep Apnea; Pathway interactions; Patients; Prostaglandins; Protocols documentation; Purpose; Relative (related person); Research; Research Personnel; Resources; Source; United States National Institutes of Health; Vasodilation; Vasodilator Agents; reactive hyperemia; response

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this study is to determine whether the relative activity of metabolic vasodilator pathways is altered in patients with obstructive sleep apnea (OSA). The specific aims of this protocol are to determine: 1) The maximal vasodilator capacity (reactive hyperemic blood flow response, RHBF); 2) The vasodilatory responses to hypoxia; 3) The effects of prostaglandin synthesis inhibition on RHBF; 4) The effects of prostaglandin synthesis inhibition on hypoxia-induced vasodilation in OSA .

这个子项目是众多研究子项目之一