Research Training in Gastroenterology

描述(由申请人提供)： UMB GI研究培训计划的目标是通过提供强调癌症遗传学和基因组学、粘膜生物学和免疫学、肠道病原体和疫苗开发以及流行病学和预防医学研究的综合跨学科课程，为胃肠病学的学术生涯培养博士后和博士后研究员。博士后实习生获得分子和细胞生物学、病理学或微生物学/免疫学的博士学位或医学博士/博士学位，博士后实习生获得流行病学和预防医学、临床研究轨道的理学硕士学位。拟议的培训将包括四个项目：癌症遗传学和基因组学、粘膜免疫学和微生物学、上皮细胞生物学以及流行病学和预防医学的临床研究培训。每个项目由一名富有成效的研究人员指导，并由专家、经验丰富的导师组成，他们在这些项目内和项目之间进行互动。我们的培训方案还受益于代表性不足的少数群体的强大代表性，特别是非裔美国人，以及高比例的女性受训人员。参加这一高度跨学科计划的部门包括内科、儿科、外科、病理学、微生物学和免疫学、生物化学和分子生物学、流行病学和预防医学、医学院的疫苗开发中心和牙学院的口腔病理学系。正如随附的申请书所示，该项目通过招聘和留住一批有才华、资金充足的教职员工而得到加强。由我们的教师培训的许多导师已经获得了学术职位，获得了同行评议的校外资金，并发表了重要的研究论文。尽管我们的教师在培训GI研究人员方面已经有了良好的记录，但在UMB仍然需要一个正式的、集成的GI培训结构，如NIDDK T32授权机制所提供的结构。在统一的框架下组织这一跨学科计划将带来以下优势：可靠的资金支持来源、对培训进展的密切监控、为GI研究方面的培训提供额外的动力，以及吸引强大的培训候选人。因此，我们提出这项申请是为了解决这些目标，并影响内科科学家和其他研究人员在胃肠病领域的短缺

DESCRIPTION (provided by applicant): The goal of the UMB GI Research Training Program is to prepare pre- and post-doctoral fellows for academic careers in Gastroenterology by offering an integrated, interdisciplinary curriculum that emphasizes cancer genetics and genomics, mucosal biology and immunology, enteric pathogens and vaccine development, and epidemiology and preventive medicine research. Pre-doctoral trainees obtain Ph.D. or combined M.D./Ph.D. degrees in Molecular and Cell Biology, Pathology, or Microbiology/Immunology, whereas postdoctoral trainees earn a Master of Science degree in Epidemiology and Preventive Medicine, Clinical Research Track. The proposed training will consist of four programs: Cancer Genetics and Genomics, Mucosal Immunology and Microbiology, Epithelial Cell Biology, and Clinical Research Training in Epidemiology and Preventive Medicine. Each program is directed by a productive investigator and consists of expert, experienced mentors who interact both within and among these programs. Our training program also benefits from strong representation of underrepresented minority groups, particularly African-Americans, and by a high proportion of female trainees. Departments represented in this highly interdisciplinary program include Medicine, Pediatrics, Surgery, Pathology, Microbiology and Immunology, Biochemistry and Molecular Biology, Epidemiology and Preventive Medicine, the Center for Vaccine Development in the Medical School, and the Department of Oral Pathology in the Dental School. As evinced in the accompanying application, this program has been strengthened by the recruitment and retention of a number of talented, well-funded faculty members. Numerous mentees trained by our faculty have proceeded to obtain academic positions, earn peer-reviewed extramural funding, and publish important research papers. Although our faculty already have a strong track record in training GI researchers, there is a need at UMB for a formalized, integrated GI training structure such as that afforded by the NIDDK T32 granting mechanism. Organization of this interdisciplinary program under one umbrella will afford the advantages of a secure source of funding support, close monitoring of training progress, additional impetus for training in GI research, and the attraction of strong training candidates. We therefore submit this application to address these goals and to impact upon the shortage of physician-scientists and other researchers in the field of Gastroenterology