HYPOGLYCEMIA AND EXERCISE IN CHILDREN AND ADOLESCENTS WITH TYPE 1 DIABETES

患有 1 型糖尿病的儿童和青少年的低血糖与运动

• 批准号: 7724986
• 负责人: PIETRO R GALASSETTI
• 金额: $ 1.88万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-12-01 至 2008-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7724986
• 关键词: Adolescent; Attenuated; Child; Clinical; Computer Retrieval of Information on Scientific Projects Database; Daily; Event; Exercise; Funding; Grant; Hypoglycemia; Incidence; Institution; Insulin-Dependent Diabetes Mellitus; Life; Patients; Research; Research Personnel; Resources; Risk; Source; United States National Institutes of Health; blood pressure regulation; cardiovascular disorder prevention; cognitive function; fetal; glycemic control; improved; insulin sensitivity; response

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The specific aim of this project is to determine whether in children/adolescents with Type 1 Diabetes, the adaptive glucoregulatory response to exercise is attenuated, contributing to the high incidence of hypoglycemia occurring in this group of patients. In the management of patients with Type 1 diabetes mellitus (T1DM), hypoglycemia is a major clinical problem. Hypoglycemia may disrupt daily activities, cause life-threatening events, induce fetal damage, alter cognitive function in children, and exert long-term negative effects on intellectual function. Hypoglycemia often occurs in association with physical exercise, often forcing patients to renounce several beneficial effects of exercise, including improved insulin sensitivity and glycemic control, and improved control of blood pressure and prevention of cardiovascular disease, for which these patients are at elevated risk.

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