Diamond-like Carbon Thin Films for Anti-fog Lens Coating in Laparoscopy

用于腹腔镜防雾镜片涂层的类金刚石碳薄膜

• 批准号: 9813323
• 负责人: JACQUELINE A JOHNSON
• 金额: $ 42.21万
• 依托单位: UNIVERSITY OF TENNESSEE SPACE INSTITUTE
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-09-01 至 2022-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9813323
• 关键词: 3T3 Cells; Adhesions; Biological Assay; Blood; Blood Platelets; Body Fluids; Bronchoscopes; Carbon; Cell Culture Techniques; Chemicals; Complement 3a; Complement Activation; Consumption; Cystoscopes; Cytoplasmic Granules; Dependence; Deposition; Diamond; Elements; Endoscopes; Ensure; Environment; Excision; Film; Fogs; Goals; Health Care Costs; Hospitals; Human body; Hydrogen Bonding; Impairment; Infection; Intervention; Irrigation; Laparoscopes; Laparoscopic Surgical Procedures; Laparoscopy; Laryngoscopes; Lasers; Liquid substance; Literature; London; Measures; Medical Technology; Membrane; Metabolic; Methods; Mucous body substance; Natural graphite; Nature; Operative Surgical Procedures; Optics; Oxygen; Patients; Physiologic pulse; Plasma; Platelet Activation; Prevention; Property; Proteins; Recovery; Research; Resistance; Silicon; Site; Surface; Surgeon; Surgical Error; Surgical incisions; Techniques; Technology; Testing; Thinness; Time; Trypan Blue; Vision; Visual impairment; Water; Work; aqueous; base; biomaterial compatibility; cell growth; college; cytotoxicity; evidence base; hydrophilicity; improved; infection risk; lens; light scattering; novel; operation; physical property; prevent; transmission process

PROJECT SUMMARY The objective of this work is to develop an antifogging coating for laparoscope lenses that will help maintain optimum viewing conditions for surgeons during laparoscopic surgery. Laparoscopes allow surgeries with smaller incisions, resulting in many benefits to the patient, including decreased recovery time. Although the laparoscope has improved many surgical procedures, a drawback is that laparoscope lenses can fog, impairing the surgeon’s vision. Laparoscope lenses are also subject to splatter by irrigation fluid and contamination by blood, mucus, and other bodily fluids. Impaired vision results in decreased precision and a greater chance of surgical error. Commonly used antifogging techniques, such as the application of antifogging solutions and pre-warming of the laparoscope, have not been proven effective. Cleaning an obscured lens typically requires removal and reinsertion, which results in surgical flow disruption and time consumption. Furthermore, the possibility of infection at the surgical site is increased with each reinsertion. The proposed research will result in a new laparoscope lens coating that will overcome current difficulties with fogging and contamination, enabling a clear field of vision during laparoscopic surgery. In addition, the coating, which is permanently applied to the lens, will protect the lens from scratching. Benefits include increased surgical precision and less potential for surgical error, improved surgical flow, decreased operating times, and lowered healthcare costs. This technology can also be applied to other related medical technologies such as laryngoscopes, bronchoscopes, cystoscopes, and endoscopes. To achieve our objective for this project, we will create novel diamond-like carbon (DLC) coatings by pulsed laser deposition. The films will be subsequently characterized to enable optimization of their properties for the prevention of fogging. DLC was chosen for this application due to its many favorable properties including scratch resistance and transparency. Special additives will be included within the coatings to make water more attractive to them, so any moisture on the surface will spread out evenly, preventing light scatter and enabling a clear view through the laparoscope lens. The coatings will also be tested to ensure that they are safe for insertion into the human body.

项目摘要 这项工作的目的是开发一种防雾涂层腹腔镜镜头，这将有助于 在腹腔镜手术期间为外科医生保持最佳的观察条件。腹腔镜允许 小切口手术，对患者有许多好处，包括减少恢复 时间虽然腹腔镜已经改善了许多外科手术，但缺点是， 腹腔镜镜头会起雾，影响外科医生的视力。腹腔镜镜头也受到 冲洗液飞溅和血液、粘液和其他体液污染。视力受损 导致精度降低和手术错误的可能性增大。常用防雾剂 诸如防雾溶液的应用和腹腔镜的预热的技术已经 没有被证明有效。清洁被遮挡的透镜通常需要移除和重新插入，这 导致手术流程中断和时间消耗。此外，感染的可能性在 手术部位随着每次重新插入而增加。 这项拟议中的研究将产生一种新的腹腔镜透镜涂层， 在腹腔镜手术期间，避免了雾化和污染的困难，使视野清晰。 此外，永久性地施加到透镜的涂层将保护透镜免受刮擦。 受益包括提高手术精度和减少手术错误的可能性，改善手术 减少手术时间，降低医疗成本。这项技术也可以应用于 其他相关的医疗技术，如喉镜，支气管镜，膀胱镜， 内窥镜 为了实现这个项目的目标，我们将通过以下方式创建新型类金刚石碳（DLC）涂层： 脉冲激光沉积随后将对膜进行表征以使其性能优化。 防止起雾的性能。DLC被选择用于此应用，因为它具有许多有利的特性， 包括耐刮擦性和透明性的性能。特殊添加剂将包括在 涂层使水对它们更有吸引力，因此表面上的任何水分都会均匀地扩散， 防止光散射并能够通过腹腔镜透镜清晰地观察。涂层还将 进行测试，以确保它们可以安全地插入人体。