Diamond-like Carbon Thin Films for Anti-fog Lens Coating in Laparoscopy
Diamond-like Carbon Thin Films for Anti-fog Lens Coating in Laparoscopy
批准号:
9813323
负责人:
JACQUELINE A JOHNSON
金额:
$42.21万
依托单位国家:
美国
项目类别:
财政年份:
2019
资助国家:
美国
项目状态:
已结题
起止时间:
2019-09-01 至 2022-08-31
关键词:
3T3 CellsAdhesionsBiological AssayBloodBlood PlateletsBody FluidsBronchoscopesCarbonCell Culture TechniquesChemicalsComplement 3aComplement ActivationConsumptionCystoscopesCytoplasmic GranulesDependenceDepositionDiamondElementsEndoscopesEnsureEnvironmentExcisionFilmFogsGoalsHealth Care CostsHospitalsHuman bodyHydrogen BondingImpairmentInfectionInterventionIrrigationLaparoscopesLaparoscopic Surgical ProceduresLaparoscopyLaryngoscopesLasersLiquid substanceLiteratureLondonMeasuresMedical TechnologyMembraneMetabolicMethodsMucous body substanceNatural graphiteNatureOperative Surgical ProceduresOpticsOxygenPatientsPhysiologic pulsePlasmaPlatelet ActivationPreventionPropertyProteinsRecoveryResearchResistanceSiliconSiteSurfaceSurgeonSurgical ErrorSurgical incisionsTechniquesTechnologyTestingThinnessTimeTrypan BlueVisionVisual impairmentWaterWorkaqueousbasebiomaterial compatibilitycell growthcollegecytotoxicityevidence basehydrophilicityimprovedinfection risklenslight scatteringnoveloperationphysical propertypreventtransmission process
中文摘要
项目总结
这项工作的目的是开发一种用于腹腔镜镜片的防雾涂层,这将有助于
在腹腔镜术中为外科医生保持最佳的观察条件。腹腔镜允许
小切口的手术,给病人带来了许多好处,包括减少了恢复
时间到了。尽管腹腔镜术改进了许多外科手术,但缺点是
腹腔镜镜片会产生雾气,损害外科医生的视力。腹腔镜片也会受到
灌注液的飞溅以及血液、粘液和其他体液的污染。视力受损
结果导致精确度降低,手术出错的可能性更大。常用防雾剂
技术,如应用防雾剂和预热腹腔镜,有
没有被证明是有效的。清洁模糊的镜片通常需要取出并重新插入,这
导致手术流程中断和时间消耗。此外,感染的可能性在
手术部位随着每一次再植入而增加。
这项拟议的研究将产生一种新的腹腔镜镜片涂层,它将克服目前
不易产生雾气和污染,可在腹腔镜手术中提供清晰的视野。
此外,永久涂在镜片上的涂层将保护镜片不被刮伤。
好处包括提高了手术精确度,减少了手术失误的可能性,改进了手术
减少了运营时间,降低了医疗保健成本。这项技术也可以应用于
其他相关医疗技术,如喉镜、支气管镜、膀胱镜和
内窥镜。
为了实现这个项目的目标,我们将通过以下方式创建新型类金刚石(DLC)涂层
脉冲激光沉积。随后将对薄膜进行表征,以使其能够优化其
防雾性能。DLC之所以被选作这一应用,是因为它具有许多优点
性能包括耐刮擦性和透明性。特殊添加剂将包括在
涂层使水对它们更具吸引力,因此表面的任何水分都会均匀分布,
防止光散射,通过腹腔镜片获得清晰的视野。涂层还将
接受测试,以确保它们可以安全地植入人体。
英文摘要
PROJECT SUMMARY
The objective of this work is to develop an antifogging coating for laparoscope lenses that will help
maintain optimum viewing conditions for surgeons during laparoscopic surgery. Laparoscopes allow
surgeries with smaller incisions, resulting in many benefits to the patient, including decreased recovery
time. Although the laparoscope has improved many surgical procedures, a drawback is that
laparoscope lenses can fog, impairing the surgeon’s vision. Laparoscope lenses are also subject to
splatter by irrigation fluid and contamination by blood, mucus, and other bodily fluids. Impaired vision
results in decreased precision and a greater chance of surgical error. Commonly used antifogging
techniques, such as the application of antifogging solutions and pre-warming of the laparoscope, have
not been proven effective. Cleaning an obscured lens typically requires removal and reinsertion, which
results in surgical flow disruption and time consumption. Furthermore, the possibility of infection at the
surgical site is increased with each reinsertion.
The proposed research will result in a new laparoscope lens coating that will overcome current
difficulties with fogging and contamination, enabling a clear field of vision during laparoscopic surgery.
In addition, the coating, which is permanently applied to the lens, will protect the lens from scratching.
Benefits include increased surgical precision and less potential for surgical error, improved surgical
flow, decreased operating times, and lowered healthcare costs. This technology can also be applied
to other related medical technologies such as laryngoscopes, bronchoscopes, cystoscopes, and
endoscopes.
To achieve our objective for this project, we will create novel diamond-like carbon (DLC) coatings by
pulsed laser deposition. The films will be subsequently characterized to enable optimization of their
properties for the prevention of fogging. DLC was chosen for this application due to its many favorable
properties including scratch resistance and transparency. Special additives will be included within the
coatings to make water more attractive to them, so any moisture on the surface will spread out evenly,
preventing light scatter and enabling a clear view through the laparoscope lens. The coatings will also
be tested to ensure that they are safe for insertion into the human body.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Transformative Iron Metal Nanoparticles with Controlled Oxidation for Magnetic Particle Imaging.
-
批准号:10730728
-
项目类别:
-
资助金额:$45.11万
-
财政年份:2023
-
负责人:JACQUELINE A JOHNSON
-
依托单位:
ADVANCED HIGH-RESOLUTION TWO-DIMENSIONAL X-RAY DETECTOR FOR MAMMOGRAPHY
-
批准号:7991368
-
项目类别:
-
资助金额:$36.48万
-
财政年份:2008
-
负责人:JACQUELINE A JOHNSON
-
依托单位:
ADVANCED HIGH-RESOLUTION TWO-DIMENSIONAL X-RAY DETECTOR FOR MAMMOGRAPHY
-
批准号:7560050
-
项目类别:
-
资助金额:$49.29万
-
财政年份:2008
-
负责人:JACQUELINE A JOHNSON
-
依托单位:
ADVANCED HIGH-RESOLUTION TWO-DIMENSIONAL X-RAY DETECTOR FOR MAMMOGRAPHY
-
批准号:7743431
-
项目类别:
-
资助金额:$36.71万
-
财政年份:2008
-
负责人:JACQUELINE A JOHNSON
-
依托单位:
ADVANCED HIGH-RESOLUTION TWO-DIMENSIONAL X-RAY DETECTOR FOR MAMMOGRAPHY
-
批准号:8046190
-
项目类别:
-
资助金额:$0.93万
-
财政年份:2008
-
负责人:JACQUELINE A JOHNSON
-
依托单位:
ADVANCED HIGH-RESOLUTION TWO-DIMENSIONAL X-RAY DETECTOR FOR MAMMOGRAPHY
-
批准号:7386471
-
项目类别:
-
资助金额:$53.47万
-
财政年份:2008
-
负责人:JACQUELINE A JOHNSON
-
依托单位:
LOW FRICTION COATINGS ON GLASS AND CERAMICS
-
批准号:7001866
-
项目类别:
-
资助金额:$0.52万
-
财政年份:2005
-
负责人:JACQUELINE A JOHNSON
-
依托单位:
ADVANCED HIGH-RESOLUTION TWO-DIMENSIONAL X-RAY DETECTOR
-
批准号:6734393
-
项目类别:
-
资助金额:$25.94万
-
财政年份:2003
-
负责人:JACQUELINE A JOHNSON
-
依托单位:
ADVANCED HIGH-RESOLUTION TWO-DIMENSIONAL X-RAY DETECTOR
-
批准号:6804688
-
项目类别:
-
资助金额:$22.29万
-
财政年份:2003
-
负责人:JACQUELINE A JOHNSON
-
依托单位:
MATURATIONAL CHANGE IN LANGUAGE ACQUISITION CAPACITY
-
批准号:2203131
-
项目类别:
-
资助金额:$11.08万
-
财政年份:1994
-
负责人:JACQUELINE A JOHNSON
-
依托单位:
MATURATIONAL CHANGE IN LANGUAGE ACQUISITION CAPACITY
-
批准号:2203130
-
项目类别:
-
资助金额:$11.19万
-
财政年份:1994
-
负责人:JACQUELINE A JOHNSON
-
依托单位:
MATURATIONAL CHANGE IN LANGUAGE ACQUISITION CAPACITY
-
批准号:2203132
-
项目类别:
-
资助金额:$1.46万
-
财政年份:1994
-
负责人:JACQUELINE A JOHNSON
-
依托单位:
海外基金