Diamond-like Carbon Thin Films for Anti-fog Lens Coating in Laparoscopy
Diamond-like Carbon Thin Films for Anti-fog Lens Coating in Laparoscopy
批准号:
9813323
负责人:
JACQUELINE A JOHNSON
金额:
$42.21万
依托单位国家:
美国
项目类别:
财政年份:
2019
资助国家:
美国
项目状态:
已结题
起止时间:
2019-09-01 至 2022-08-31
关键词:
3T3 CellsAdhesionsBiological AssayBloodBlood PlateletsBody FluidsBronchoscopesCarbonCell Culture TechniquesChemicalsComplement 3aComplement ActivationConsumptionCystoscopesCytoplasmic GranulesDependenceDepositionDiamondElementsEndoscopesEnsureEnvironmentExcisionFilmFogsGoalsHealth Care CostsHospitalsHuman bodyHydrogen BondingImpairmentInfectionInterventionIrrigationLaparoscopesLaparoscopic Surgical ProceduresLaparoscopyLaryngoscopesLasersLiquid substanceLiteratureLondonMeasuresMedical TechnologyMembraneMetabolicMethodsMucous body substanceNatural graphiteNatureOperative Surgical ProceduresOpticsOxygenPatientsPhysiologic pulsePlasmaPlatelet ActivationPreventionPropertyProteinsRecoveryResearchResistanceSiliconSiteSurfaceSurgeonSurgical ErrorSurgical incisionsTechniquesTechnologyTestingThinnessTimeTrypan BlueVisionVisual impairmentWaterWorkaqueousbasebiomaterial compatibilitycell growthcollegecytotoxicityevidence basehydrophilicityimprovedinfection risklenslight scatteringnoveloperationphysical propertypreventtransmission process
中文摘要
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英文摘要
PROJECT SUMMARY
The objective of this work is to develop an antifogging coating for laparoscope lenses that will help
maintain optimum viewing conditions for surgeons during laparoscopic surgery. Laparoscopes allow
surgeries with smaller incisions, resulting in many benefits to the patient, including decreased recovery
time. Although the laparoscope has improved many surgical procedures, a drawback is that
laparoscope lenses can fog, impairing the surgeon’s vision. Laparoscope lenses are also subject to
splatter by irrigation fluid and contamination by blood, mucus, and other bodily fluids. Impaired vision
results in decreased precision and a greater chance of surgical error. Commonly used antifogging
techniques, such as the application of antifogging solutions and pre-warming of the laparoscope, have
not been proven effective. Cleaning an obscured lens typically requires removal and reinsertion, which
results in surgical flow disruption and time consumption. Furthermore, the possibility of infection at the
surgical site is increased with each reinsertion.
The proposed research will result in a new laparoscope lens coating that will overcome current
difficulties with fogging and contamination, enabling a clear field of vision during laparoscopic surgery.
In addition, the coating, which is permanently applied to the lens, will protect the lens from scratching.
Benefits include increased surgical precision and less potential for surgical error, improved surgical
flow, decreased operating times, and lowered healthcare costs. This technology can also be applied
to other related medical technologies such as laryngoscopes, bronchoscopes, cystoscopes, and
endoscopes.
To achieve our objective for this project, we will create novel diamond-like carbon (DLC) coatings by
pulsed laser deposition. The films will be subsequently characterized to enable optimization of their
properties for the prevention of fogging. DLC was chosen for this application due to its many favorable
properties including scratch resistance and transparency. Special additives will be included within the
coatings to make water more attractive to them, so any moisture on the surface will spread out evenly,
preventing light scatter and enabling a clear view through the laparoscope lens. The coatings will also
be tested to ensure that they are safe for insertion into the human body.
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