Tennessee Valley Cooperative Human Tissue Network

田纳西谷合作人体组织网络

基本信息

项目摘要

DESCRIPTION (provided by applicant): The Cooperative Human Tissue Network (CHTN) has played an important role since 1987 as a source of human tissues to support biomedical research. As the Western Division of the CHTN, we propose to continue to serve the scientific community by procuring and distributing biospecimens in an efficient, cost-effective manner. The specific aims of this application are: 1) To collect, process and distribute high quality human solid tissue and biofluid specimens with appropriate clinical annotation to qualified researchers on a prospective basis; 2) To apply a rigorous Quality Management System to all aspects of the program; 3) To provide tumor macrodissection, tissue microarray "build on demand" and RNA/DNA extraction services, as requested; 4) To collect and bank pre-neoplastic and rare lesions to facilitate basic research in tumor progression and early translational research; 5) To protect patient confidentiality by obtaining informed consent for collection of extraneous tissue and biofluids for research, and through de-identification of specimens, and by continuing to partner with VUMC patient advocates to engage patients and provide opportunities for participation in research; 6) To develop and integrate new business models and informatics (IT) strategies that improve operational efficiency, by developing a third generation network Investigator IT system for request sharing; 7) To develop innovative internal IT programs by partnering with VUMC BioVu project to link tissue samples to large clinical datasets, and by providing an internal mechanism for research results sharing at VUMC as a pilot program; 8) To expand CHTN marketing and education efforts through strategies to increase awareness in the scientific community. In 12 years as a CHTN Division, we have been an innovative and highly productive member of the network, distributing over 63,170 specimens to 723 investigators in the last 5 years. We have developed critical SOPs and integrative biorepository software that have been implemented throughout the CHTN. Our goals in the next funding period include continuing to provide numerous high quality biospecimens and to develop innovative IT programs to improve efficiency and communication within the network and with investigators.
描述(由申请人提供):自1987年以来,合作人体组织网络(CHTN)作为支持生物医学研究的人体组织来源发挥了重要作用。作为CHTN的西部分部,我们建议继续以高效,具有成本效益的方式采购和分发生物标本,为科学界服务。该应用的具体目标是:1)收集、处理和分配高质量的人力资源 2)将严格的质量管理体系应用于项目的各个方面; 3)根据要求提供肿瘤宏观解剖、组织微阵列“按需构建”和RNA/DNA提取服务; 4)收集和储存癌前病变和罕见病变,以促进肿瘤进展的基础研究和早期转化研究; 5)通过获取知情同意书以收集用于研究的外来组织和生物流体,以及通过去除标本的身份,保护患者的机密性,并继续与VUMC患者倡导者合作,让患者参与并提供参与研究的机会; 6)通过开发第三代网络Investigator IT系统,开发和整合新的业务模式和信息技术战略,以提高运营效率; 7)通过与VUMC BioVu项目合作,将组织样本与大型临床数据集联系起来,并作为试点计划,为VUMC的研究成果共享提供内部机制,从而开发创新的内部IT计划; 8)通过提高科学界认识的战略,扩大CHTN的营销和教育工作。 在12年的CHTN部门,我们一直是网络的创新和高生产力的成员,在过去的5年中分发超过63,170标本723调查。我们已经开发了关键的SOP和综合生物储存库软件,并已在整个CHTN实施。我们在下一个资助期的目标包括继续提供大量高质量的生物标本,并开发创新的IT计划,以提高网络内以及与研究人员的效率和沟通。

项目成果

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MARY Kay WASHINGTON其他文献

MARY Kay WASHINGTON的其他文献

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{{ truncateString('MARY Kay WASHINGTON', 18)}}的其他基金

Core 1: Tissue Pathology and Cellular Analysis
核心 1:组织病理学和细胞分析
  • 批准号:
    10443608
  • 财政年份:
    2019
  • 资助金额:
    $ 98.9万
  • 项目类别:
Core 1: Tissue Pathology and Cellular Analysis
核心 1:组织病理学和细胞分析
  • 批准号:
    10218106
  • 财政年份:
    2019
  • 资助金额:
    $ 98.9万
  • 项目类别:
Core 1: Tissue Pathology and Cellular Analysis
核心 1:组织病理学和细胞分析
  • 批准号:
    10700840
  • 财政年份:
    2019
  • 资助金额:
    $ 98.9万
  • 项目类别:
Tennessee Valley Cooperative Human Tissue Network
田纳西谷合作人体组织网络
  • 批准号:
    9899210
  • 财政年份:
    2014
  • 资助金额:
    $ 98.9万
  • 项目类别:
Tennessee Valley Cooperative Human Tissue Network
田纳西谷合作人体组织网络
  • 批准号:
    10577781
  • 财政年份:
    2014
  • 资助金额:
    $ 98.9万
  • 项目类别:
Tennessee Valley Cooperative Human Tissue Network
田纳西谷合作人体组织网络
  • 批准号:
    10378774
  • 财政年份:
    2014
  • 资助金额:
    $ 98.9万
  • 项目类别:
Tennessee Valley Cooperative Human Tissue Network
田纳西谷合作人体组织网络
  • 批准号:
    8669436
  • 财政年份:
    2014
  • 资助金额:
    $ 98.9万
  • 项目类别:
Gastric Histopathology Core
胃组织病理学核心
  • 批准号:
    8413060
  • 财政年份:
    2013
  • 资助金额:
    $ 98.9万
  • 项目类别:
Gastric Histopathology Core
胃组织病理学核心
  • 批准号:
    8632354
  • 财政年份:
    2009
  • 资助金额:
    $ 98.9万
  • 项目类别:
Gastric Histopathology Core
胃组织病理学核心
  • 批准号:
    8990359
  • 财政年份:
    2009
  • 资助金额:
    $ 98.9万
  • 项目类别:

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