Skeletal Biology and Biomechanics (SBB) Core

加州大学旧金山分校肌肉骨骼生物学和医学核心中心骨骼生物学和生物力学 (SBB)核心支持一个庞大而强大的研究人员基础。这个多样化的基础和临床 研究人员对了解肌肉骨骼健康和疾病做出了重大贡献。 然而，这些和其他研究人员正在进行的研究工作仍然不足以防止迅速 在我们的老龄化人口中，许多后天性肌肉骨骼疾病的发生率越来越高。因此，加速度 因此，迫切需要开展一系列研究，以促进骨骼疾病的预防和治疗。解决方案将 需要采用更加系统的方法，采用综合研究战略和调查人员群体。到 为了迎接这一挑战，SBB核心通过提供综合的，成本- 有效和高效地获得严格的肌肉骨骼生物学和生物力学服务。SBB核心 服务和培养跨多个校区和学科的肌肉骨骼研究社区， 为用户提供无缝访问服务，核心站点位于两个主园区，轻松的数字会议， 和多个地点的活动。SBB核心的成功实施预计不仅 降低研究费用，提高数据的产量和质量，同时也能产生稳健的深入研究 通过整合肌肉骨骼生物学的不同方面来分析样品和动物模型， 生物力学核心采用复杂而强大的新服务将简化定量 分析肌肉骨骼组织，以补充和鼓励急需的大数据应用 接近这个领域。通过培训和教育，SBB核心将促进新的 研究人员到外地，并将培养一个社区的多才多艺的肌肉骨骼研究人员与广泛的一套， 技能和批判性思维。

The UCSF Core Center for Musculoskeletal Biology and Medicine Skeletal Biology and Biomechanics (SBB) Core supports a large and robust research base of investigators. This diverse group of basic and clinical investigators has made major contributions to the understanding of musculoskeletal health and disease. However, the ongoing research efforts by these and other investigators remain insufficient to prevent the rapidly increasing occurrence of many acquired musculoskeletal diseases in our aging population. Thus, acceleration of research that advances the prevention and treatment of skeletal diseases is urgently needed. Solutions will require a more systems-based approach with integrated research strategies and investigator communities. To meet this challenge, the SBB Core facilitates musculoskeletal research at UCSF by providing integrated, cost- effective, and efficient access to rigorous musculoskeletal biology and biomechanics services. The SBB Core serves and cultivates the musculoskeletal research community across multiple campuses and disciplines by offering users seamless access to services, with Core sites at the two main campuses, easy digital conferencing, and events at multiple locations. The successful implementation of the SBB Core is anticipated to not only reduce research expenses and increase the output and quality of data, but also to produce robust in-depth analyses of samples and animal models through integration of different aspects of musculoskeletal biology and biomechanics. The Core’s adoption of sophisticated and powerful new services will streamline quantitative analyses of musculoskeletal tissues to complement and encourage the much-needed application of big data approaches to this field. Through training and education, the SBB Core will promote the entry of new investigators to the field and will foster a community of versatile musculoskeletal researchers with a broad set of skills and critical thinking.