Skeletal Biology and Biomechanics (SBB) Core

加州大学旧金山分校肌肉骨骼生物学和医学核心中心骨骼生物学和生物力学 (SBB)Core支持庞大而强大的研究人员基础。这一多样化的基础和临床群体 研究人员为了解肌肉骨骼健康和疾病做出了重大贡献。 然而，这些和其他调查人员正在进行的研究努力仍然不足以防止迅速 在我们老龄化的人口中，许多获得性肌肉骨骼疾病的发生率越来越高。因此，加速 迫切需要更多的研究来推进骨骼疾病的预防和治疗。解决方案将 需要更多以系统为基础的方法，并整合研究战略和研究人员社区。至 面对这一挑战，SBB Core通过提供集成的、成本低廉的 有效、高效地获得严格的肌肉骨骼生物学和生物力学服务。SBB核心 为跨多个校区和学科的肌肉骨骼研究社区提供服务和培养 通过两个主校区的核心站点，为用户提供无缝的服务访问、轻松的数字会议、 以及多个地点的活动。SBB核心的成功实施预计不仅将 减少研究费用，提高数据的产量和质量，但也能产生强大的深度 通过整合肌肉骨骼生物学和生物医学的不同方面对样本和动物模型进行分析 生物力学。核心采用复杂而强大的新服务将简化量化 对肌肉骨骼组织进行分析，以补充和鼓励急需的大数据应用 这一领域的研究方法。通过培训和教育，SBB核心将促进新的 研究人员到现场，并将培养一个多才多艺的肌肉骨骼研究人员社区，拥有广泛的 技能和批判性思维。

The UCSF Core Center for Musculoskeletal Biology and Medicine Skeletal Biology and Biomechanics (SBB) Core supports a large and robust research base of investigators. This diverse group of basic and clinical investigators has made major contributions to the understanding of musculoskeletal health and disease. However, the ongoing research efforts by these and other investigators remain insufficient to prevent the rapidly increasing occurrence of many acquired musculoskeletal diseases in our aging population. Thus, acceleration of research that advances the prevention and treatment of skeletal diseases is urgently needed. Solutions will require a more systems-based approach with integrated research strategies and investigator communities. To meet this challenge, the SBB Core facilitates musculoskeletal research at UCSF by providing integrated, cost- effective, and efficient access to rigorous musculoskeletal biology and biomechanics services. The SBB Core serves and cultivates the musculoskeletal research community across multiple campuses and disciplines by offering users seamless access to services, with Core sites at the two main campuses, easy digital conferencing, and events at multiple locations. The successful implementation of the SBB Core is anticipated to not only reduce research expenses and increase the output and quality of data, but also to produce robust in-depth analyses of samples and animal models through integration of different aspects of musculoskeletal biology and biomechanics. The Core’s adoption of sophisticated and powerful new services will streamline quantitative analyses of musculoskeletal tissues to complement and encourage the much-needed application of big data approaches to this field. Through training and education, the SBB Core will promote the entry of new investigators to the field and will foster a community of versatile musculoskeletal researchers with a broad set of skills and critical thinking.