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National Alzheimer's Coordinating Center

国家阿尔茨海默病协调中心

基本信息

批准号：
10415065
负责人：
Walter Anthony Kukull
金额：
$ 784.6万
依托单位：
UNIVERSITY OF WASHINGTON
依托单位国家：
美国
项目类别：
财政年份：
2021
资助国家：
美国
起止时间：
2021-06-15 至 2026-05-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10415065
关键词：
Achievement Adoption Age Alzheimer disease prevention Alzheimer&apos s Disease Alzheimer&apos s disease related dementia Applied Research Area Award Big Data Biological Markers Biometry Collaborations Communication Complex Consultations Contracts Data Data Collection Data Coordinating Center Data Science Data Set Databases Dementia Early Diagnosis Enrollment Environment Faculty Funding Future Genetic Genetic Diseases Genomics Goals Heterogeneity Individual Informatics Infrastructure Institutes Lead Leadership Link Medicine Methodology Methods Mission Modernization Peer Review Positioning Attribute Publications Recording of previous events Research Research Peer Review Research Personnel Research Support Resources Risk Factors Sampling Scientist Secure Services Source Specimen Standardization Techniques Technology Testing Time Translational Research Universities Washington base career clinical database clinical examination cohort community center data access data resource data sharing data storage site data visualization deep learning digital disease heterogeneity e-science experience high standard imaging biomarker improved innovation instrument interest interoperability meetings neuroimaging neuropathology novel programs repository social media success tool translational health science trend web site

项目摘要

Project summary/abstract NACC (as U01 AG016976, at University of Washington) has been active since 1999. The existing NACC infrastructure is described in the Facilities and Resources Section of this application. The broad goals of the past funding cycles are consistent with those of the current U24 RFA — that is, to serve as: a.) the central hub for organizing and enabling communication within and outside of the ADRC program, including annual meetings and steering committees; b.) a national data resource, collecting data from the Alzheimer's Disease Research Centers (ADRCs) as well as affiliated data and sample repositories; and c.) a facilitator of current and future AD/ADRD research. NACC has considerable experience and success in reaching these goals, and is positioned for continued success in a rapidly advancing field. New data and methods are appearing in areas such as biomarkers, neuropathology, and tests for early detection. Through the strategic adoption of technological advances, we will build on these accomplishments at an accelerated pace. Building on our already significant capabilities, we will: promote and broaden communication within and outside of the ADRC program; expand informatics capabilities of NACC consistent with FAIR principles; conduct and support methodologic and applied research, leveraging deep expertise in biostatistics and data science; and support early-career research scientists by providing peer-reviewed competitive funding for several “junior investigators” each year. We aim to continue to improve our approach in each arena by combining time-tested approaches with the new tools and innovations we are developing to meet the changing scientific, technological, and communication needs of the NIA ADRC program and the field.

项目总结/文摘