Leadership and Administrative Core

在美国，阿尔茨海默病（AD）是一个日益严重的重大公共卫生危机，并且日益严重

Alzheimer’s disease (AD) is a major and increasing public health crisis in the United States (US) and a growing health disparity, with African Americans (AAs) at disproportionate risk for AD and related dementias (ADRD) compared to non-Hispanic Whites.1, 2 We seek to build on the experience of an interdisciplinary team in AD/ADRD-relevant research to support diverse early career researchers and mid-career scientists newly transitioning into AD/ADRD-relevant research carrying out research of high quality intended to prevent cognitive and functional decline in minority older adults and reduce racial disparities of AD/ADRD. The faculty of this AD-RCMAR are from the Johns Hopkins Schools of Public Health, Nursing, and Medicine, Morgan State University, and Hampton University and have decades of experience working with African American, Hispanic, and Asian American older adults, and the community organizations that serve them. All are nationally recognized mentors with substantial experience training under-represented minority scholars. The overall aims for this renewal application of the Leadership and Administrative Core (LAC) are to provide governance and administration of the Center, to facilitate the training and development of RCMAR Scientists from underrepresented backgrounds, and to advance the field of minority aging research on AD/ADRD. The LAC will provide essential leadership and structure for this AD-RCMAR and its mentoring, data collection, analysis, intervention, implementation, and dissemination activities, providing coordination and integration across the Cores and Pilot Studies, while maintaining communications with the RCMAR Coordinating Center, other NIA Research Centers, and external funding and oversight entities. The LAC will work closely with the Research Education Component, Community-Liaison and Recruitment Core, and the Analysis Core to accomplish these aims, thereby advancing our understanding of social and behavioral aspects of minority aging to ameliorate disparities relevant to AD/ADRD. The MPI’s (Drs. Thorpe and Gallo) will be responsible for oversight of all Center activities to ensure accountability and responsiveness to evolving scientific opportunities and public health needs, including quality control of research, protection of human research participants, supervision of administrative functions, fiscal oversight, interfacing with the External Advisory Committee, and liaison with grant agencies and officials of Johns Hopkins University and participating Centers and Universities.