Stress and Mortality Among Black Men

黑人的压力和死亡率

• 批准号: 10288167
• 负责人: ROLAND J. THORPE
• 金额: $ 15.42万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-04-01 至 2023-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10288167
• 关键词: Address; Affect; African American; Age; Aging; American; Area; Attention; Award; Behavioral; Biological; Biological Factors; Biological Markers; Biology; Cognition; Data; Data Set; Development; Economics; Environment; Environmental Risk Factor; Epidemiologist; Family; Foundations; Future; Gap Junctions; Gender; Genes; Genetic; Genomics; Geriatrics; Gerontology; Goals; Health; Health and Retirement Study; Health behavior; Immune; Independent Scientist Award; Inflammation; Inflammatory; Institution; Knowledge; Lead; Life Expectancy; Link; Longevity; Modeling; Neighborhoods; Neurosecretory Systems; Outcome; Pathway interactions; Pattern; Physiological; Play; Policy Maker; Positioning Attribute; Psychosocial Factor; Public Health Schools; Quality of life; Race; Research; Research Activity; Research Personnel; Research Project Grants; Risk; Role; Scientist; Social Behavior; Societies; Socioeconomic Status; Stress; Structure; Subgroup; System; Testing; Time; Training; Training Activity; Work; base; behavioral economics; biobehavior; biopsychosocial; black men; black women; career; career development; comparative; coping; design; development policy; economic determinant; effective intervention; experience; functional outcomes; health disparity; healthy aging; improved; interest; lens; male health; men; middle age; mortality; novel; programs; psychologic; psychosocial; racial and ethnic; response; social; social factors; stressor; success

PROJECT SUMMARY Black men age-adjusted mortality rate in 2014 was 21.1 percent higher than white men. While several factors have been hypothesized to account for these differences, stress has been noted as a key determinant of Black men's health. Because of its unique position at the nexus of social factors; psychological coping; and the associated physiologic response, stress is an ideal pathway for understanding health disparities. However, stress and its downstream consequences have received relatively little attention as it relates to Black men's mortality. Over the last four years, I having been building a program of research examining social, behavioral and economic determinants of Black men's health which serves as a foundation for this mid-career Independent Scientist (K02) award application. I have two immediate career objectives. First, I want to advance my career by integrating biomarker and genetic data into my existing research portfolio to better understand the basic mechanisms of Black men's stress, and mortality (Aim 1). Second, I want to apply the biopsychosocial model for explaining links between stress and mortality in Black men (Aim 2). My long-term career objective is to establish a national network of scholars who share similar research interest and create a center on men's health and aging (Aim 3). The K02 mechanism would provide me the protected time to achieve my immediate and long-term career goals. To assist in accomplishing my aims, I will be supported by an interdisciplinary group of world renown scholars who work spans a variety of fields including health of Black Americans, biology of stress, inflammation, cognition, biomarker data, longitudinal data, mortality, gerontology and geriatrics. Further I have the support of the Department of Health, Behavior, and Society at Johns Hopkins Bloomberg School of Public Health. The proposed research and training activities have the potential to propel me from being a mid-career scientist to an independent investigator in the area of Black Men's Health and mortality. Findings from the K02 will be used to inform subsequent research objectives to address unique risks associated with health and functional outcomes to inform policy makers of the evidence for the development of policy relevant solutions for Black men. My ability to conduct high level research and effectively collaborate positions me to take full advantage of what the K02 mechanism offers.

项目总结 2014年，黑人男性的年龄调整死亡率比白人男性高21.1%。虽然有几个因素 都被认为是解释这些差异的原因，压力被认为是黑人的关键决定因素 男人的健康。因为它在社会因素的联系中的独特地位；心理应对；以及 相关的生理反应，压力是了解健康差异的理想途径。然而， 压力及其下游后果相对较少受到关注，因为它与黑人男性的 死亡率。在过去的四年里，我一直在建立一个研究项目，考察社会、行为 以及黑人男性健康的经济决定因素，这是职业生涯中期的基础 独立科学家(K02)奖项申请。我有两个直接的职业目标。首先，我想要 通过将生物标记物和基因数据整合到我现有的研究组合中来推进我的职业生涯，以更好地 了解黑人男性压力和死亡率的基本机制(目标1)。第二，我想要应用 解释黑人男性压力和死亡率之间联系的生物心理社会模型(目标2)。我的长期生活 职业目标是建立一个由具有相似研究兴趣的学者组成的全国性网络，并创建 以男性健康和老龄化为中心(目标3)。K02机制将为我提供受保护的时间 实现我近期和长期的职业目标。为了帮助实现我的目标，我将得到 一个由世界知名学者组成的跨学科小组，他们的工作涉及多个领域，包括黑人健康 美国人，压力生物学，炎症，认知，生物标记物数据，纵向数据，死亡率，老年学 还有老年病。此外，我还得到了约翰斯卫生、行为和社会部的支持 霍普金斯大学彭博公共卫生学院。拟议的研究和培训活动具有潜力 推动我从职业生涯中期的科学家成为黑人健康领域的独立调查员 和死亡率。来自K02的研究结果将被用于为后续研究目标提供信息，以解决独特的 与健康和功能结果相关的风险，以向政策制定者通报 为黑人男子制定与政策相关的解决方案。我能够进行高水平的研究，并有效地 Collaboration使我能够充分利用K02机制提供的功能。