Stress and Mortality Among Black Men

项目摘要 2014年，黑人男性年龄调整后的死亡率比白色男性高出21.1%。虽然有几个因素 已经假设这些差异，压力已被视为黑色的关键决定因素 男人的健康。由于其在社会因素、心理应对和 与生理反应相关，压力是了解健康差异的理想途径。但是，在这方面， 压力及其下游后果受到的关注相对较少，因为它与黑人男性的 mortality.在过去的四年里，我一直在建立一个研究项目， 黑人男性健康的经济决定因素，这是这个职业生涯中期的基础。 独立科学家奖（K02）。我有两个职业目标。首先我想 通过将生物标志物和遗传数据整合到我现有的研究组合中， 了解黑人男性的压力和死亡率的基本机制（目标1）。第二，我想应用 生物心理社会模型解释压力和黑人男性死亡率之间的联系（目标2）。我的长期 职业目标是建立一个全国性的学者网络，他们有着相似的研究兴趣，并创造一个 以男性健康和衰老为中心（目标3）。K02机制会给我提供保护时间， 实现我的近期和长期职业目标。为了帮助实现我的目标，我将得到以下方面的支持： 一个由世界知名学者组成的跨学科小组，他们的工作跨越了包括黑人健康在内的各个领域。 美国人，压力生物学，炎症，认知，生物标志物数据，纵向数据，死亡率，老年学 和老年医学此外，我还得到了约翰大学健康、行为和社会系的支持。 霍普金斯布隆伯格公共卫生学院。拟议的研究和培训活动有可能 推动我从一个职业生涯中期的科学家成为黑人男性健康领域的独立调查员， and mortality. K02的发现将用于为后续研究目标提供信息，以解决独特的 与健康和功能结果相关的风险，以便向决策者通报 为黑人制定相关政策解决方案。我进行高水平研究的能力， 协作使我能够充分利用K02机制所提供的优势。

PROJECT SUMMARY Black men age-adjusted mortality rate in 2014 was 21.1 percent higher than white men. While several factors have been hypothesized to account for these differences, stress has been noted as a key determinant of Black men's health. Because of its unique position at the nexus of social factors; psychological coping; and the associated physiologic response, stress is an ideal pathway for understanding health disparities. However, stress and its downstream consequences have received relatively little attention as it relates to Black men's mortality. Over the last four years, I having been building a program of research examining social, behavioral and economic determinants of Black men's health which serves as a foundation for this mid-career Independent Scientist (K02) award application. I have two immediate career objectives. First, I want to advance my career by integrating biomarker and genetic data into my existing research portfolio to better understand the basic mechanisms of Black men's stress, and mortality (Aim 1). Second, I want to apply the biopsychosocial model for explaining links between stress and mortality in Black men (Aim 2). My long-term career objective is to establish a national network of scholars who share similar research interest and create a center on men's health and aging (Aim 3). The K02 mechanism would provide me the protected time to achieve my immediate and long-term career goals. To assist in accomplishing my aims, I will be supported by an interdisciplinary group of world renown scholars who work spans a variety of fields including health of Black Americans, biology of stress, inflammation, cognition, biomarker data, longitudinal data, mortality, gerontology and geriatrics. Further I have the support of the Department of Health, Behavior, and Society at Johns Hopkins Bloomberg School of Public Health. The proposed research and training activities have the potential to propel me from being a mid-career scientist to an independent investigator in the area of Black Men's Health and mortality. Findings from the K02 will be used to inform subsequent research objectives to address unique risks associated with health and functional outcomes to inform policy makers of the evidence for the development of policy relevant solutions for Black men. My ability to conduct high level research and effectively collaborate positions me to take full advantage of what the K02 mechanism offers.