Stress and Mortality Among Black Men

黑人的压力和死亡率

• 批准号: 9914962
• 负责人: ROLAND J. THORPE
• 金额: $ 22.15万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-04-01 至 2023-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9914962
• 关键词: Address; Affect; African American; Age; Aging; American; Area; Attention; Award; Behavioral; Biological; Biological Factors; Biological Markers; Biology; Cognition; Data; Data Set; Development; Economics; Environment; Environmental Risk Factor; Epidemiologist; Family; Foundations; Future; Gap Junctions; Gender; Genes; Genetic; Genomics; Geriatrics; Gerontology; Goals; Health; Health and Retirement Study; Health behavior; Immune; Independent Scientist Award; Inflammation; Inflammatory; Institution; Knowledge; Lead; Life Expectancy; Link; Longevity; Modeling; Neighborhoods; Neurosecretory Systems; Outcome; Pathway interactions; Pattern; Physiological; Play; Policy Maker; Positioning Attribute; Psychosocial Factor; Public Health Schools; Quality of life; Race; Research; Research Activity; Research Personnel; Research Project Grants; Risk; Role; Scientist; Social Behavior; Societies; Socioeconomic Status; Stress; Structure; Subgroup; System; Testing; Time; Training; Training Activity; Woman; Work; base; behavioral economics; biobehavior; biopsychosocial; career; career development; comparative; coping; design; development policy; economic determinant; effective intervention; experience; functional outcomes; health disparity; healthy aging; improved; interest; lens; male health; men; middle age; mortality; novel; programs; psychologic; psychosocial; racial and ethnic; response; social; social factors; stressor; success

PROJECT SUMMARY Black men age-adjusted mortality rate in 2014 was 21.1 percent higher than white men. While several factors have been hypothesized to account for these differences, stress has been noted as a key determinant of Black men's health. Because of its unique position at the nexus of social factors; psychological coping; and the associated physiologic response, stress is an ideal pathway for understanding health disparities. However, stress and its downstream consequences have received relatively little attention as it relates to Black men's mortality. Over the last four years, I having been building a program of research examining social, behavioral and economic determinants of Black men's health which serves as a foundation for this mid-career Independent Scientist (K02) award application. I have two immediate career objectives. First, I want to advance my career by integrating biomarker and genetic data into my existing research portfolio to better understand the basic mechanisms of Black men's stress, and mortality (Aim 1). Second, I want to apply the biopsychosocial model for explaining links between stress and mortality in Black men (Aim 2). My long-term career objective is to establish a national network of scholars who share similar research interest and create a center on men's health and aging (Aim 3). The K02 mechanism would provide me the protected time to achieve my immediate and long-term career goals. To assist in accomplishing my aims, I will be supported by an interdisciplinary group of world renown scholars who work spans a variety of fields including health of Black Americans, biology of stress, inflammation, cognition, biomarker data, longitudinal data, mortality, gerontology and geriatrics. Further I have the support of the Department of Health, Behavior, and Society at Johns Hopkins Bloomberg School of Public Health. The proposed research and training activities have the potential to propel me from being a mid-career scientist to an independent investigator in the area of Black Men's Health and mortality. Findings from the K02 will be used to inform subsequent research objectives to address unique risks associated with health and functional outcomes to inform policy makers of the evidence for the development of policy relevant solutions for Black men. My ability to conduct high level research and effectively collaborate positions me to take full advantage of what the K02 mechanism offers.

项目摘要 2014年，黑人年龄调整后的死亡率比白人高21.1％。而几个因素 已经假设要考虑到这些差异，压力已被认为是黑色的关键决定因素 男性健康。由于其在社会因素的联系中的独特地位；心理应对；和 相关的生理反应，压力是理解健康差异的理想途径。然而， 压力及其下游后果与黑人有关 死亡。在过去的四年中，我一直在构建研究社会，行为的研究计划 和黑人健康的经济决定因素，这是该中期职业的基础 独立科学家（K02）奖励申请。我有两个直接的职业目标。首先，我想 通过将生物标志物和遗传数据整合到我现有的研究组合中以更好地提高我的职业生涯 了解黑人压力和死亡率的基本机制（AIM 1）。第二，我想应用 生物心理社会模型，用于解释黑人男性压力与死亡率之间的联系（AIM 2）。我的长期 职业目标是建立一个具有类似研究兴趣并创造一个学者的国家网络 男子健康与衰老中心（AIM 3）。 K02机制将为我提供受保护的时间 实现我的直接和长期职业目标。为了帮助实现我的目标，我将得到我的支持 一个跨学科的世界著名学者，他们的工作涵盖了各种领域，包括黑人健康 美国人，压力生物学，炎症，认知，生物标志物数据，纵向数据，死亡率，老年学 和老年医学。此外，我得到了约翰斯卫生，行为和社会部的支持 霍普金斯彭博公共卫生学院。拟议的研究和培训活动有潜力 将我从黑人健康领域的独立调查员推向医生中期科学家 和死亡率。 K02的发现将用于告知随后的研究目标以解决独特 与健康和功能结果相关的风险，以告知决策者证据 制定黑人政策相关解决方案。我进行高水平研究并有效的能力 协作位置使我充分利用K02机制提供的优势。