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Bacterial Phenotypic Diversity

Bacterial Phenotypic Diversity
细菌表型多样性
批准号：
7675874
负责人：
Colin Manoil
金额：
$28.58万
依托单位：
UNIVERSITY OF WASHINGTON
依托单位国家：
美国
项目类别：
财政年份：
2009
资助国家：
美国
项目状态：
已结题
起止时间：
2009-04-20 至 2014-02-28
来源：
https://reporter.nih.gov/project-details/7675874
关键词：
AchievementAllelesAnti-Bacterial AgentsAntibiotic ResistanceAntibioticsBase SequenceBiological AssayBurkholderia pseudomalleiCenters of Research ExcellenceDatabasesDiagnosticDiagnostic testsDiseaseDrug Delivery SystemsEmerging Communicable DiseasesExhibitsGenerationsGenesGeneticGenomeGenomicsGoalsGrowthImage AnalysisInfectionLaboratoriesLibrariesMediatingMelioidosisMethodsMicroarray AnalysisMusMutationOrganismPathogenesisPhenotypePhysiologicalProceduresPropertyRegulationResearchResistanceScreening procedureStressTechnologyTestingVariantVirulenceWorkbasebiodefensebiological adaptation to stressclinically relevantinsightmutantnew technologynovelresearch studystress tolerancetechnology developmenttrait

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中文摘要
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英文摘要
The primary goal of the research is to identify the FT and BP genes responsible for several intrinsic antibiotic resistance, virulence and stress tolerance traits. The results should provide mechanistic insights into the physiological basis of each and may identify potential antibacterial drug targets. An additional set of experiments will help define BP species diversity in these and other phenotypes, and may identify diagnostic tests to differentiate natural isolates. As part of the project, a new-generation sequencing-based technology for assessing the makeup of transposon mutant pools of will be developed.
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Defining the antibiotic intrinsic resistome of Acinetobacter baumannii
  • 批准号：
    10220708
  • 项目类别：
  • 资助金额：
    $27.21万
  • 财政年份：
    2019
  • 负责人：
    Colin Manoil
  • 依托单位：
    UNIVERSITY OF WASHINGTON
Defining the antibiotic intrinsic resistome of Acinetobacter baumannii
  • 批准号：
    10064113
  • 项目类别：
  • 资助金额：
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  • 财政年份：
    2019
  • 负责人：
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  • 依托单位：
    UNIVERSITY OF WASHINGTON
Targeting chronic Pseudomonas aeruginosa wound infections
  • 批准号：
    8509966
  • 项目类别：
  • 资助金额：
    $23.01万
  • 财政年份：
    2013
  • 负责人：
    Colin Manoil
  • 依托单位：
    UNIVERSITY OF WASHINGTON
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  • 批准号：
    8626358
  • 项目类别：
  • 资助金额：
    $19.02万
  • 财政年份：
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  • 负责人：
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  • 依托单位：
    UNIVERSITY OF WASHINGTON
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