课题基金 / 基金详情

Genome wide profiling of histone variants in tumors

Genome wide profiling of histone variants in tumors
肿瘤中组蛋白变异的全基因组分析
批准号：
10014570
负责人：
YAMINI P DALAL
金额：
$45.93万
依托单位：
DIVISION OF BASIC SCIENCES - NCI
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/10014570
关键词：
AddressAdult GlioblastomaAreaAutomobile DrivingChromosomal InstabilityChromosomal translocationCoupledEpigenetic ProcessFailureGenesGenomeHistonesHumanLeadLocationMachine LearningMalignant NeoplasmsMapsMicroscopyOutcomePathway interactionsPatientsPublicationsPublishingResolutionSamplingSolid NeoplasmSpecificityTimeUntranslated RNAVariantWorkcancer cellcentromere protein Afollow-upgenome-widenew technologyrepairedsmall molecule inhibitortumorvirtual

项目摘要

项目成果

YAMINI P DALAL的其他基金

相似基金

相关文献

中文摘要
翻译
点击翻译按钮获取中文摘要
英文摘要
We are currently focused on analysis of chromosome translocations and mechanisms involved in the breaks and repair machinery involved in the translocations. Using high resolution microscopy coupled to machine learning, we are currently finding new ways to automatically score patient samples for translocations involving the CENP-A domain we mapped in previous publications, and using small molecule inhibitors that can disrupt these pathways. These translocations and amplifications occur in virtually every time of solid tumor we have examined, including adult glioblastomas, which is currently a focus in the lab.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Analysis of centromere identity and structure in human cells
  • 批准号：
    8553040
  • 项目类别：
  • 资助金额：
    $30.55万
  • 财政年份：
    --
  • 负责人：
    YAMINI P DALAL
  • 依托单位：
    DIVISION OF BASIC SCIENCES - NCI
Genome wide profiling of histone variants in tumors
  • 批准号：
    8938009
  • 项目类别：
  • 资助金额：
    $36.81万
  • 财政年份：
    --
  • 负责人：
    YAMINI P DALAL
  • 依托单位：
    DIVISION OF BASIC SCIENCES - NCI
Analysis of centromere identity and structure in human cells
  • 批准号：
    10014571
  • 项目类别：
  • 资助金额：
    $47.33万
  • 财政年份：
    --
  • 负责人：
    YAMINI P DALAL
  • 依托单位：
    DIVISION OF BASIC SCIENCES - NCI
Analysis of centromere identity and structure in human cells
  • 批准号：
    7966218
  • 项目类别：
  • 资助金额：
    $31.78万
  • 财政年份：
    --
  • 负责人：
    YAMINI P DALAL
  • 依托单位：
    DIVISION OF BASIC SCIENCES - NCI
海外基金