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Genome wide profiling of histone variants in colorectal cancer cells

Genome wide profiling of histone variants in colorectal cancer cells
结直肠癌细胞组蛋白变异的全基因组分析
批准号:
8157698
负责人:
YAMINI P DALAL
金额:
$47.43万
依托单位国家:
美国
项目类别:
财政年份:
--
资助国家:
美国
项目状态:
未结题
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英文摘要
We have mapped a unique histone variant genome wide in colorectal cancer cell lines and found that it is clustered tightly at epigenetically distinctive regions. We have mapped these regions further using cytological methods and found a subset that enriched in regions implicated in tumor biology. Future goals involve mapping histone variants in tumors in order to track progression of aberrant chromatin structures as a consequence of the tumorigenic process, and discovering remodelers and processes involved in the mis-localization.
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Analysis of centromere identity and structure in human cells
  • 批准号:
    7966218
  • 项目类别:
  • 资助金额:
    $31.78万
  • 财政年份:
    --
  • 负责人:
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  • 依托单位:
Genome wide profiling of histone variants in tumors
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Analysis of centromere identity and structure in human cells
  • 批准号:
    8553040
  • 项目类别:
  • 资助金额:
    $30.55万
  • 财政年份:
    --
  • 负责人:
    YAMINI P DALAL
  • 依托单位:
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  • 批准号:
    10014571
  • 项目类别:
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  • 财政年份:
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  • 负责人:
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  • 依托单位:
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