Translational Research in Biomaterials

生物材料转化研究

• 批准号: 10259674
• 负责人: MARK W. GRINSTAFF
• 金额: $ 19.97万
• 依托单位: BOSTON UNIVERSITY (CHARLES RIVER CAMPUS)
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-09-09 至 2022-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10259674
• 关键词: Biocompatible Materials; Translational Research

ABSTRACT This application proposes the second renewal of Boston University's NIH training program, Translational Research in Biomaterials (TRB). The mission of the TRB is to develop PhD students into interdisciplinary and translational research scientists and engineers. Through their TRB training, students acquire a fundamental and quantitative understanding of materials, surface science, biomaterial-tissue response, and molecular and cell biology, as well as training experiences in interdisciplinary programs that promote discussion and scientific inquiry in areas outside students’ “comfort zones.” New for this renewal are: a junior faculty mentoring plan, integrated student governance, better data collection, and more targeted efforts for underrepresented minority recruitment. Furthermore, we expand the educational, research, and training opportunities for TRB Fellows to include BU’s NSF ERC in Cellular Metamaterials and partnerships with Massachusetts General Hospital and Beth Israel Deaconess Medical Center. The cornerstones of the TRB program are the curriculum and the program elements that combine interdisciplinary research, quantitative science, engineering, and translational-based courses in clinical trials and business, with student-organized seminar club, dinners with clinicians, training in professional ethics, individual career plans, and professional development workshops. Our aim is to teach the unique skills and competencies that are essential to thrive in a multidisciplinary collaborative team striving to meet common goals in research, development, translation, and, ultimately, commercialization. Since 2009, the BU TRB has had 35 interdisciplinary trainees (15 women, 20 men; 26% minority; 97% retention; 100% employment; 5.1 years average PhD completion; 14 graduates and 20 current students, one of whom will graduate next month) who have excelled on multiple fronts, including publishing papers (99), filing patents (7), oral (47) and poster (155) presentations at local and national meetings, and participating in societal / community activities (e.g., President of the BU Student Association of Graduate Engineers, tutoring for high school students, etc.). All trainees have been supported after their TRB funding ended through independently written fellowships (one NIH NRSA F31, one NIH NRSA F30, seven NSF GRFP awards, one US Pharmacopeial Global Fellowship Award, one CIMIT Engineering Fellowship, one Glacier NSF GK12 Fellowship, one BUnano Cross- Disciplinary Fellowship, one Clare Booth Luce Fellowship, and one Ford Foundation Fellowship) or the NIH R21 / R01 grants of their mentors. In this renewal, the continuation of the TRB, with eight trainees per year funded via NIH, is aligned with the expertise of participating faculty, the availability of a large and strong applicant pool eligible for and interested in the TRB program, and an extramural funding base to provide the appropriate research environment and continued support for NIH trainees beyond their first two years supported by the TRB.

抽象的 该申请提出了波士顿大学NIH培训计划的第二次续签，《翻译》 生物材料研究（TRB）。 TRB的任务是将博士生发展成跨学科 并翻译了研究科学家和工程师。通过他们的TRB培训，学生获得了 对材料，表面科学，生物材料组织反应的基本和定量理解以及 分子和细胞生物学以及跨学科计划的培训经验 在学生“舒适区域”外的地区进行讨论和科学询问。此续约的新事物是：大三 教师心理计划，综合学生治理，更好的数据收集以及更多针对性的努力 代表性不足的少数民族招聘。此外，我们扩展了教育，研究和培训 TRB研究员将BU的NSF ERC包括在细胞超材料中，并与 马萨诸塞州综合医院和贝丝以色列执事医疗中心。 TRB计划的基石是课程和结合的程序元素 临床试验中的跨学科研究，定量科学，工程和基于翻译的课程 和业务，与学生组织的开创性俱乐部，与临床医生一起晚餐，职业道德培训， 个人职业计划和专业发展研讨会。我们的目标是教授独特的技能和 在多学科合作团队中蓬勃发展的能力，以满足共同的能力 研究，开发，翻译以及最终商业化的目标。自2009年以来，BU TRB具有 有35名跨学科的学员（15名女性，20名男性；少数26％；保留97％； 100％就业； 5.1 年平均博士学位完成； 14名毕业生和20名学生，其中一名将于下个月毕业） 在多个方面的出色表现，包括出版论文（99），申请专利（7），口头（47）和海报 （155）在当地和国家会议上的演讲，并参加社会 /社区活动（例如 BU学生协会研究生工程师协会主席，高中生的辅导等）。全部 在TRB资金通过独立书面奖学金结束后，受训人员得到了支持（一个 NIH NRSA F31，一个NIH NRSA F30，七项NSF GRFP奖，一项美国药物全球奖学金 奖项，一项CIMIT工程奖学金，一个冰川NSF GK12奖学金，一个Bunano Cross- 纪律奖学金，一个克莱尔摊位卢斯奖学金和一项福特基金会奖学金）或NIH R21 / R01导师的赠款。 在此续约中，TRB的延续，每年通过NIH资助八名学员，与 参与教师的专业知识，有资格并有兴趣的大型且强大的申请人池的可用性 在TRB计划中，以及提供适当的研究环境和 除了TRB支持的头两年之外，对NIH受训者的持续支持。