Translational Research in Biomaterials

生物材料转化研究

基本信息

项目摘要

ABSTRACT This application proposes the second renewal of Boston University's NIH training program, Translational Research in Biomaterials (TRB). The mission of the TRB is to develop PhD students into interdisciplinary and translational research scientists and engineers. Through their TRB training, students acquire a fundamental and quantitative understanding of materials, surface science, biomaterial-tissue response, and molecular and cell biology, as well as training experiences in interdisciplinary programs that promote discussion and scientific inquiry in areas outside students’ “comfort zones.” New for this renewal are: a junior faculty mentoring plan, integrated student governance, better data collection, and more targeted efforts for underrepresented minority recruitment. Furthermore, we expand the educational, research, and training opportunities for TRB Fellows to include BU’s NSF ERC in Cellular Metamaterials and partnerships with Massachusetts General Hospital and Beth Israel Deaconess Medical Center. The cornerstones of the TRB program are the curriculum and the program elements that combine interdisciplinary research, quantitative science, engineering, and translational-based courses in clinical trials and business, with student-organized seminar club, dinners with clinicians, training in professional ethics, individual career plans, and professional development workshops. Our aim is to teach the unique skills and competencies that are essential to thrive in a multidisciplinary collaborative team striving to meet common goals in research, development, translation, and, ultimately, commercialization. Since 2009, the BU TRB has had 35 interdisciplinary trainees (15 women, 20 men; 26% minority; 97% retention; 100% employment; 5.1 years average PhD completion; 14 graduates and 20 current students, one of whom will graduate next month) who have excelled on multiple fronts, including publishing papers (99), filing patents (7), oral (47) and poster (155) presentations at local and national meetings, and participating in societal / community activities (e.g., President of the BU Student Association of Graduate Engineers, tutoring for high school students, etc.). All trainees have been supported after their TRB funding ended through independently written fellowships (one NIH NRSA F31, one NIH NRSA F30, seven NSF GRFP awards, one US Pharmacopeial Global Fellowship Award, one CIMIT Engineering Fellowship, one Glacier NSF GK12 Fellowship, one BUnano Cross- Disciplinary Fellowship, one Clare Booth Luce Fellowship, and one Ford Foundation Fellowship) or the NIH R21 / R01 grants of their mentors. In this renewal, the continuation of the TRB, with eight trainees per year funded via NIH, is aligned with the expertise of participating faculty, the availability of a large and strong applicant pool eligible for and interested in the TRB program, and an extramural funding base to provide the appropriate research environment and continued support for NIH trainees beyond their first two years supported by the TRB.
摘要

项目成果

期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)

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MARK W. GRINSTAFF其他文献

MARK W. GRINSTAFF的其他文献

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{{ truncateString('MARK W. GRINSTAFF', 18)}}的其他基金

R21: A novel antibody-drug conjugate for treatment of squamous cell lung carcinoma
R21:一种用于治疗鳞状细胞肺癌的新型抗体药物偶联物
  • 批准号:
    10510002
  • 财政年份:
    2022
  • 资助金额:
    $ 19.97万
  • 项目类别:
R21: A novel antibody-drug conjugate for treatment of squamous cell lung carcinoma
R21:一种用于治疗鳞状细胞肺癌的新型抗体药物偶联物
  • 批准号:
    10671669
  • 财政年份:
    2022
  • 资助金额:
    $ 19.97万
  • 项目类别:
The Conundrum of Absentee Receptors: Efficacy Potentiation Through Drug-Receptor Modulation
缺失受体的难题:通过药物受体调节增强功效
  • 批准号:
    10708018
  • 财政年份:
    2022
  • 资助金额:
    $ 19.97万
  • 项目类别:
Sustained Release Relaxin-2 for the Treatment of Frozen Shoulder
缓释松弛素2治疗肩周炎
  • 批准号:
    10443323
  • 财政年份:
    2022
  • 资助金额:
    $ 19.97万
  • 项目类别:
Sustained Release Relaxin-2 for the Treatment of Frozen Shoulder
缓释松弛素2治疗肩周炎
  • 批准号:
    10669219
  • 财政年份:
    2022
  • 资助金额:
    $ 19.97万
  • 项目类别:
A novel approach for reversal of autophagic defects using lysosome-targeted nanoparticles
使用溶酶体靶向纳米颗粒逆转自噬缺陷的新方法
  • 批准号:
    9914192
  • 财政年份:
    2019
  • 资助金额:
    $ 19.97万
  • 项目类别:
A novel approach for reversal of autophagic defects using lysosome-targeted nanoparticles
使用溶酶体靶向纳米颗粒逆转自噬缺陷的新方法
  • 批准号:
    9752911
  • 财政年份:
    2019
  • 资助金额:
    $ 19.97万
  • 项目类别:
R21: Acidic Nanoparticles for Restoration of Autophagy in Age-associated NAFLD
R21:酸性纳米颗粒用于恢复年龄相关性 NAFLD 中的自噬
  • 批准号:
    9902306
  • 财政年份:
    2019
  • 资助金额:
    $ 19.97万
  • 项目类别:
Dissolvable Hydrogel Dressing for the Treatment of Burns
用于治疗烧伤的可溶性水凝胶敷料
  • 批准号:
    9010534
  • 财政年份:
    2016
  • 资助金额:
    $ 19.97万
  • 项目类别:
Synthesis, Characterization, and Evaluation of Polymeric Tissue Lubricants
聚合物组织润滑剂的合成、表征和评估
  • 批准号:
    8886944
  • 财政年份:
    2014
  • 资助金额:
    $ 19.97万
  • 项目类别:

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ART: Translational Research Ambassadors Network for Strengthening Institutional Capacity and Fostering a Responsive and Open Mindset (TRANSFORM)
ART:加强机构能力和培养积极响应和开放心态的转化研究大使网络(TRANSFORM)
  • 批准号:
    2331208
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    2024
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Conference: Workshop on Translational Research on Data Heterogeneity
会议:数据异构性转化研究研讨会
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    2406154
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    2024
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Translational Research and Implementation Science for Nurses (TRAIN) Program 2.0
护士转化研究和实施科学 (TRAIN) 计划 2.0
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    10680769
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    2023
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Clinical and Translational Science Collaborative of Northern Ohio, An Intensive Summer Education Program in Translational Research for Underrepresented Students (INSPIRE-US)
俄亥俄州北部的临床和转化科学合作组织,针对代表性不足的学生的转化研究强化暑期教育项目 (INSPIRE-US)
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    2023
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南卡罗来纳州临床
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    10637143
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    2023
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The ANTIDOTE Institute- Advancing New Toxicology Investigators in Drug abuse and Original Translational research Efforts
ANTIDOTE Institute - 推动新毒理学研究人员在药物滥用和原创转化研究工作中的发展
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