Center for Cellular Metabolism Research in Oklahoma
俄克拉荷马州细胞代谢研究中心
基本信息
- 批准号:10090975
- 负责人:
- 金额:$ 262.2万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2021
- 资助国家:美国
- 起止时间:2021-02-05 至 2026-01-31
- 项目状态:未结题
- 来源:
- 关键词:AddressAgingAreaArthritisAutoimmune DiseasesBiological ModelsBiology of AgingBiomedical ResearchCardiovascular DiseasesCardiovascular systemCellsCenters of Research ExcellenceClinical ImmunologyCore FacilityDevelopmentDiabetes MellitusDiseaseEnvironmentEquipmentFacultyFosteringFoundationsFundingGoalsGrowthHealthHuman ResourcesInfrastructureInterdisciplinary StudyLeadershipLifeMalignant NeoplasmsMedical ResearchMentorsMetabolismOklahomaPathogenesisPhaseRecordsResearchResearch InfrastructureResearch InstituteResearch PersonnelResourcesScientistSecureTrainingUniversitiesWorkcareercollaborative environmentenvironmental changeexperienceinterestmembermultidisciplinarynovelprofessorprogramsrecruitrepairedsuccesstenure track
项目摘要
Altered cellular metabolism contributes to the pathogenesis of many common diseases, such as cardiovascular
disease, cancer, diabetes, and autoimmune disorders, which are prevalent in Oklahoma. However, metabolism-
related research resources and infrastructure are currently insufficient and scattered in Oklahoma. To address
these deficiencies, this Center for Cellular Metabolism Research in Oklahoma (CMRO) Phase I COBRE will
create and nurture excellence in cellular metabolism in Oklahoma. The CMRO is located at the Oklahoma
Medical Research Foundation (OMRF), a leading biomedical research institute. The central focus of the CMRO
is to support five new Assistant Member-level faculty (equivalent to tenure-track Assistant Professor at a
Research University) as Project Leaders from three different OMRF Research Programs: Cardiovascular Biology
(CVB), Aging & Metabolism (AM), and Arthritis & Clinical Immunology (ACI). These new junior investigators are
the foundation for expansion and unification of cellular metabolism research. They will receive an appropriate
level and form of multidisciplinary mentoring from experienced and competitive scientists. The CMRO COBRE
aims to develop a critical mass of investigators who can secure external funding to support their research while
creating a new, exciting, multidisciplinary, and collaborative environment for sustained competitive research on
cellular metabolism in Oklahoma, which will be achieved through five Aims: 1) Support five promising young
Project Leaders to scientific independence through incorporation of cellular metabolism research in their labs; 2)
Promote novel multidisciplinary research focusing on cellular metabolism through mentoring the junior Project
Leaders from three different OMRF Research Programs; 3) Integrate existing and new resources through Core
facilities that support cellular metabolism research; 4) Promote an environment that supports the success and
development of an independent sustainable center. The COBRE support will be critical to create a new,
multidisciplinary and collaborative environment for sustained competitive research on cellular metabolism in
Oklahoma.
改变的细胞代谢有助于许多常见疾病的发病机制,如心血管疾病,
疾病、癌症、糖尿病和自身免疫性疾病,这些疾病在俄克拉荷马州普遍存在。然而,新陈代谢-
相关的研究资源和基础设施目前不足,分散在俄克拉荷马州。解决
这些不足之处,这个俄克拉荷马州细胞代谢研究中心(CMRO)第一阶段COBRE将
在俄克拉荷马州创造和培养卓越的细胞代谢。CMRO位于俄克拉荷马州
医学研究基金会(OMRF),一个领先的生物医学研究机构。CMRO的核心焦点
是支持五个新的助理教授级教师(相当于终身助理教授在一个
作为项目负责人,来自三个不同的OMRF研究项目:心血管生物学
(CVB)老化与代谢(AM)和关节炎与临床免疫学(ACI)。这些新的初级调查员是
为细胞代谢研究的扩展和统一奠定了基础。他们将得到适当的
由经验丰富和有竞争力的科学家提供多学科指导的水平和形式。CMRO COBRE
旨在培养一批能够获得外部资金支持其研究的关键调查人员,
创造一个新的,令人兴奋的,多学科和协作的环境,持续的竞争性研究,
细胞代谢在俄克拉荷马州,这将通过五个目标实现:1)支持五个有前途的年轻
通过在实验室中纳入细胞代谢研究,项目领导人可以实现科学独立性; 2)
通过指导初级项目,促进以细胞代谢为重点的新的多学科研究
来自三个不同OMRF研究项目的领导者; 3)通过核心整合现有和新的资源
支持细胞代谢研究的设施; 4)促进支持成功的环境,
建立独立的可持续发展中心。COBRE的支持对于创建一个新的,
多学科和协作环境的持续竞争性研究细胞代谢,
俄克拉荷马州。
项目成果
期刊论文数量(0)
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科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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{{ truncateString('Lijun Xia', 18)}}的其他基金
Center for Cellular Metabolism Research in Oklahoma
俄克拉荷马州细胞代谢研究中心
- 批准号:
10797920 - 财政年份:2021
- 资助金额:
$ 262.2万 - 项目类别:
Center for Cellular Metabolism Research in Oklahoma
俄克拉荷马州细胞代谢研究中心
- 批准号:
10399960 - 财政年份:2021
- 资助金额:
$ 262.2万 - 项目类别:
Center for Cellular Metabolism Research in Oklahoma
俄克拉荷马州细胞代谢研究中心
- 批准号:
10853688 - 财政年份:2021
- 资助金额:
$ 262.2万 - 项目类别:
Center for Cellular Metabolism Research in Oklahoma
俄克拉荷马州细胞代谢研究中心
- 批准号:
10571889 - 财政年份:2021
- 资助金额:
$ 262.2万 - 项目类别:
Center for Cellular Metabolism Research in Oklahoma
俄克拉荷马州细胞代谢研究中心
- 批准号:
10339346 - 财政年份:2021
- 资助金额:
$ 262.2万 - 项目类别:
Site-1 protease-mediated lipid metabolism in lymphatic vascular development
位点 1 蛋白酶介导的淋巴血管发育中的脂质代谢
- 批准号:
10400114 - 财政年份:2020
- 资助金额:
$ 262.2万 - 项目类别:
Site-1 protease-mediated lipid metabolism in lymphatic vascular development
位点 1 蛋白酶介导的淋巴管发育中的脂质代谢
- 批准号:
10629188 - 财政年份:2020
- 资助金额:
$ 262.2万 - 项目类别:
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