Diversity Supplement to Urban Greenness and Cardiovascular Health

城市绿化和心血管健康的多样性补充

基本信息

批准号：
10598172
负责人：
Aruni Bhatnagar
金额：
$ 15.13万
依托单位：
UNIVERSITY OF LOUISVILLE
依托单位国家：
美国
项目类别：
财政年份：
2018
资助国家：
美国
起止时间：
2018-07-01 至 2024-03-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10598172
关键词：
Adopted Affect Air Air Pollutants Air Pollution Area Biochemical Biological Markers Blood Carbon Black Cardiovascular Diseases Cardiovascular Physiology Cardiovascular system Characteristics Chronic Disease Cities Communities Data Developed Countries Developing Countries Development Ecosystem Environment Evaluation Exposure to Formulation Grasslands Green space Hair Health Health Policy Heart Hospital Mortality Hospitalization Human Individual Intervention Intervention Trial Kentucky Lead Life Expectancy Link Location Maintenance Measurement Measures Mediating Modeling Neighborhoods Noise Outcome Ozone Particulate Perception Physiological Plants Poaceae Pollution Population Prevalence Prevention strategy Psychosocial Stress Public Health Questionnaires Reporting Research Risk Risk Factors Sampling Severities Stress Sulfate Sunlight Surface Surveys Testing Trees Ultrafine Urban Community Urine Vascular Plant Wood material Work air filtration built environment cardiovascular disorder prevention cardiovascular disorder risk cardiovascular health cohort demographics design fine particles foot insight land use mortality pollutant premature prevent psychologic recruit residence social social cohesion trial design urban area urban setting urinary volatile organic compound

项目摘要

Abstract Extensive research suggests that components of the natural environment have profound effects on human health. In particular, individuals living in areas of low pollution and high levels of vegetation have been reported to have a lower burden of cardiovascular disease (CVD). Although many studies have shown that exposure to air pollution increases CVD risk and mortality, the impact of greenspaces and vegetation on CVD has not been directly studied. Hence to assess the impact of greenery on cardiovascular health and disease risk, we will conduct a pragmatic, interventional trial designed to test the hypothesis that exposure to neighborhood greenspaces diminishes CVD risk by decreasing the levels of local air pollution. To test this hypothesis, we will first evaluate baseline cardiovascular health in 16 residential neighborhood clusters with sparse greenspaces (Aim 1). In these areas, we will measure the levels of greenery, air pollution, noise and traffic, and determine how these neighborhood characteristics are associated with hospital admissions, as well as cardiovascular and all-cause mortality. To acquire individual level data, we will recruit 700 area residents and assess their cardiovascular health as well as psychosocial stress. Then, in 8 “target” clusters, we will plant nearly 8,000 established trees (Aim 2). There will be no deliberate change in greenspace in the 8 “control” clusters. Following the greening intervention, we will determine how an increase in greenspaces within the target clusters affects air pollution levels, hospital admissions and mortality, and how the greening intervention affects CVD risk and psychosocial stress within this community in comparison with the control area (Aim 3). Completion of this project would provide a new understanding of the link between urban greenspaces and cardiovascular health, and might lead to the development of new strategies to prevent CVD and to decrease the levels of urban air pollution. Importantly, the results of the project will lead to the development of a comprehensive model that could be readily adopted by cities throughout the world to create urban environments that are more conducive to human health.

抽象的广泛的研究表明，自然环境的组成部分具有深远的影响关于人类健康。特别是，生活在低污染和高水平的地区据报道，植被的心血管疾病（CVD）燃烧较低。虽然许多研究表明，暴露于空气污染会增加CVD风险和死亡率，绿空间和植被对CVD的影响尚未直接研究。因此要评估绿化对心血管健康和疾病风险的影响，我们将进行务实的，干预试验旨在检验暴露于邻里绿空间的假设通过降低当地空气污染水平来降低CVD风险。为了检验这一假设，我们将首先评估了16个居民稀疏邻里群集中的基线心血管健康绿色空间（AIM 1）。在这些地区，我们将测量绿化，空气污染，噪音的水平和交通，并确定这些社区特征与医院的关系入院以及心血管和全因死亡率。获取个人级别数据，我们将招募700名地区居民，并评估他们的心血管健康以及社会心理压力。然后，在8个“目标”簇中，我们将种植近8,000棵已建立的树木（AIM 2）。将有在8个“控制”集群中，没有故意改变Greenspace。跟随绿色干预措施，我们将确定目标簇内绿空间的增加如何影响空气污染水平，住院和死亡率以及绿色干预如何影响与控制区相比 3）。该项目的完成将为城市之间的联系提供新的了解绿色空间和心血管健康，可能导致发展新策略防止CVD并降低城市空气污染的水平。重要的是，项目将导致开发一个综合模型，可以很容易地采用全世界的城市创造更具向人类传导性的城市环境健康。