Internet as Supplier: Preventing Adolescent Use of Non-Medical Addictive Rx

说明(申请人提供)：青少年非医疗使用高成瘾性处方阿片类药物，如维柯丁和奥施康定；以及镇静剂，如安定和Xanax，正在增加。尽管青少年非医疗使用成瘾性处方药增加的原因尚不清楚，但我们知道，这些处方药在没有处方的情况下在互联网上广泛宣传和销售。治疗研究所和药物战略研究所在过去四年里对互联网药物销售进行了研究，我们认为“非处方药网站(NPWS)”可能是青少年使用这些药物增加的一个重要因素。目前还没有关于互联网在向没有处方的青少年提供处方药方面的作用的研究。修订后的RO1将继续我们对目前正在接受住院治疗计划的高危青少年使用互联网和其他来源购买药物的调查。我们有一个修订的30分钟数据收集方案，使用来自CASI(Meyers等人，1995-2007)的经过良好验证的项目，将通过经过良好测试和吸引人的网络界面(BubbleMonkey)对来自30个项目的2000名青少年(12-17岁)进行有目的的样本管理，在两年的数据收集期内。数据收集的目的是完全保护机密性。这项研究有三个主要目的：1.确定互联网购买是否是有严重药物滥用和成瘾问题的青少年获得药物的重要来源。在本样本中，我们将“显著”定义为患病率为20%或更高。2.确定互联网药物供应是否与努力戒毒后复发的很大比例有关。同样，我们在操作上将“显著”定义为患病率为20%或更高。3.为了探索互联网网站和其他来源的使用是否随着这些高危青少年的人口统计和药物使用特征的不同而有所不同。迫切需要关于青少年非医疗使用处方药的比率上升与互联网网站在没有处方的情况下销售这些药物之间的关系的信息。这项研究将是第一次直接从青少年那里获得有关互联网药物供应来源的信息。 与公共卫生相关：青少年非医疗使用维柯丁和奥施康定等高成瘾性处方阿片类药物以及镇静剂如安定和镇静剂的比例仍然很高。这些物质在互联网上被广泛宣传并在没有处方的情况下出售，可能会助长青少年的使用。这项研究将直接从青少年那里获得有关他们使用互联网和其他来源获取毒品的信息。

DESCRIPTION (provided by applicant): Adolescent non-medical use of highly addictive prescription opioid drugs, such as Vicodin and Oxycontin; and tranquilizers, such as Valium and Xanax, is increasing. Although the reasons for increasing adolescent non-medical use of addictive prescription drugs are not known, we do know that they are widely advertised and sold over the internet without prescription. The Treatment Research Institute and Drug Strategies have conducted research on internet drug sales for the past four years and we believe that "non-prescription websites (NPWs)" may be one important contributing factor to increasing adolescent use of these drugs. There has been no research on the role of the internet in supplying prescription medications to adolescents without a prescription. This revised RO1 will continue our investigations of the use of internet and other sources for drug purchase by high risk adolescents currently in residential treatment programs. We have a revised 30-minute data collection protocol using well-validated items from the CASI (Meyers et al., 1995 - 2007) that will be administered via a well-tested and engaging web interface (BubbleMonkey) to a purposive sample of 2000 adolescents (12 - 17) from 30 programs in a two-year data collection period. The data collection has been designed to completely protect confidentiality. The study has three primary aims: 1. To determine whether internet purchase is a significant source of drug availability for adolescents with serious substance abuse and addiction problems. We operationally define "significant" as a prevalence rate of 20 percent or higher in this sample. 2. To determine whether internet drug availability is associated with a significant proportion of relapses following efforts to stop drug use. Again, we operationally define "significant as a prevalence rate of 20 percent or higher. 3. To explore whether use of internet websites and other sources, differs as a function of demographic and drug use characteristics among these high-risk adolescents. Information is urgently needed about the relationship between rising rates of adolescent non- medical use of prescription drugs and internet websites that market those drugs without a prescription. This study will be the first to obtain this information directly from adolescents about internet sources of drug supply. PUBLIC HEALTH RELEVANCE: Adolescent non-medical use of highly addictive prescription opioid drugs, such as Vicodin and Oxycontin and tranquilizers such as Valium and Xanax, continues at high levels. These substances are widely advertised and sold over the internet without prescription, perhaps fostering adolescent use. This study will obtain information directly from adolescents about their use of the internet and other sources to obtain drugs.