HRS 2010 Data Collection Supplement

描述（由申请人提供）：健康与退休研究（NLA U 01 AG 009740）的本修订申请（以前称为竞争性补充）建议在2010年从2006年首次接受这些测量的HRS样本的一半（N~ 9，282）中收集和分发生物标志物和心理社会数据的第一次重复纵波。2006年，健康与退休研究引入了一种新的面对面访谈设计，包括身体表现测量，人体测量，血压，HbAlc，总胆固醇和HDL胆固醇以及C反应蛋白的干血斑测定，DNA收集，社会保障同意请求和自我管理的心理社会问卷（增强的面对面访谈）。一半的样本在2006年第一次接受采访，2007年年中公布了数据，另一半将在2008年接受采访。在以人口为基础的调查中收集身体测量和生物标志物仍然是相对较新的，很少有研究在多个时间点对同一个人进行重复测量。目前在美国没有全国代表性的样本，提供关于这些生物标志物和老年人群性能指标的个人水平变化的信息。2010年拟议的数据收集将使研究人员能够分析这些措施的稳定性和变化，将变化与其他生活环境和健康事件联系起来，并研究如何在各项措施中发生变化。这将进一步加强人力资源调查与英国老龄化纵向研究（艾尔莎）以及其他已开始采用相同方案的国际研究的可比性。此外，补编还建议在其他高度优先领域开展适度的新活动，例如利用现有的医疗保险联系，深入研究人力资源系统中的小组减员问题，并进一步扩大雇主和养恤金计划的联系，以研究退休问题。相关性（参见说明）：新的措施允许详细评估肥胖和代谢综合征的水平和变化，提供了一个无与伦比的个人和队列的变化在肥胖“流行病”。“他们还讨论了认知和身体功能随年龄的下降，包括虚弱的概念，以及这些个体变化的轨迹如何随着教育和医学进步的改善而改变。沿着现有的HRS措施和改进的心理健康措施，它们将允许对社会经济地位影响健康差异的途径进行更丰富的分析。 这是健康和退休研究（MRS）的17-22年的竞争延续申请。我们建议继续按照上一次更新中的稳态设计收集核心数据，包括在2010年增加一个新的队列;在我们对痴呆症患病率的子研究的基础上，检查发病率;增加生物样本的收集，包括DNA和心理社会内容;并继续使用关于特别专题的邮寄调查，包括继续对大约一半的抽样进行消费和时间使用的纵向计量，作为对核心数据收集的低成本补充。本申请涵盖2006年1月至2011年12月31日期间。HRS为研究老龄化的健康、经济和人口统计学的科学和政策研究人员提供了一个独特的、丰富的、具有全国代表性的纵向数据集。它提供了一个研究数据库，可以同时支持美国50岁以上人口的横截面描述，在相当长的一段时间内对给定队列的纵向研究以及对跨队列趋势的研究。到2010年，HRS将能够支持1992年、1998年和2004年进入50岁的人的健康、劳动力供应或财富积累轨迹的跨队列比较。HRS项目创建了一个超出核心调查数据的数据系统。这一扩展数据系统的一个组成部分包括与行政数据的链接，包括社会保障收入和福利记录、医疗保险使用和诊断记录、雇主养老金记录和国家死亡指数。我们计划扩大这些联系，包括从最小数据集的养老院居民的信息，并探讨与医疗补助记录的联系。第二个组成部分是使用HRS调查作为抽样框架，以支持针对特定疾病或主题领域的深入子研究。HRS数据系统的第三个方面，这不是HRS项目的正式组成部分，是在其他国家出现了一套老龄化纵向研究，这些研究有意识地设计，以产生尽可能与HRS收集的数据可比的数据。HRS提供公共使用数据，旨在让美国科学界的全部力量和创造力来应对人口老龄化的挑战。HRS正在通过研究者发起的研究对老龄化研究产生重大影响，该研究使用HRS作为研究人员或授权机构的免费投入。

DESCRIPTION (provided by applicant): This revision application (formerly called competing supplement) to the Health and Retirement Study (NLA U01AG009740) proposes to collect and distribute the first repeat longitudinal wave of biomarker and psychosocial data in 2010 from the half of the HRS sample that first received those measures in 2006 (N~9,282). In 2006, the Health and Retirement Study introduced a new in-person interview design that includes physical performance measures, anthropometric measures, blood pressure, dried blood spot assays for HbAlc, total and HDL cholesterol, and C-reactive protein, DNA collection, Social Security consent request, and a self-administered psychosocial questionnaire (the enhanced face-to-face interview). Half the sample received this interview for the first time in 2006, with the data released in mid-2007, and the other half will receive it in 2008. Collection of physical measures and biomarkers in population-based surveys is still relatively new, and very few studies provide repeat measurements on the same individuals at multiple time points. There is currently no nationally representative sample in the United States that provides information on individual-level change in these biomarkers and performance indicators in the older population. The data collection proposed for 2010 will enable researchers to analyze stability and change in these measures, link change to other life circumstances and health events, and examine how change occurs across measures. It will further enhance the comparability of the HRS with the English Longitudinal Study of Ageing (ELSA), as well as other international studies that have started to adopt the same protocols. In addition, the supplement proposes modest new activities in other high-priority areas, such as exploiting the now- available Medicare linkage to conduct an in-depth study of panel attrition in the HRS and further extensions of employer and pension plan linkages for the study of retirement.. RELEVANCE (See instructions): The new measures permit detailed assessment of levels and change in obesity and in the metabolic syndrome, providing an unparalleled picture of individual and cohort changes in the midst of the obesity "epidemic." They also address decline in cognitive and physical function with age, including the concept of frailty, and how these trajectories of individual change may be shifting with improved education and medical advances. Along with existing HRS measures and improved measures of psychological well-being they will permit richer analysis of the pathways by which socio- economic status affects disparities in health. This is competing continuation application for Years 17-22 of the Health and Retirement Study (MRS). We propose to continue core data collection on the steady-state design laid out in the previous renewal, including the addition of a new cohort in 2010; to build on our sub-study of prevalence of dementia to examine incidence; to add the collection of biological samples, including DNA, and psychosocial content; and to continue the use of mail surveys on special topics, including continued longitudinal measurement of consumption and time use for about half of the sample, as a low-cost complement to the core data collection. This application includes the period from January, 2006 through December 31, 2011. HRS provides a uniquely rich, nationally representative longitudinal dataset for the community of scientific and policy researchers who study the health, economics and demography of aging. It provides a research data base that can simultaneously support cross-sectional descriptions of the U.S. population over the age of fifty, longitudinal studies of a given cohort over a substantial period of time and research on cross-cohort trends. By 2010 the HRS will be able to support cross-cohort comparisons of trajectories of health, labor supply, or wealth accumulation for persons who entered their 50'sin 1992, 1998 and 2004. The HRS project creates a data system extending beyond the core survey data. One component of this extended data system consists of linkages to administrative data, including Social Security earnings and benefit records, Medicare utilization and diagnostic records, employer pension records, and the National Death Index. We plan to expand these linkages to include information on nursing home residents from the Minimum Data Set, and to explore linkages to Medicaid records. A second component is the use of the HRS survey as a sampling frame to support in-depth sub-studies targeted on specific diseases or topic areas. A third aspect of the HRS data system, which is not formally part of the HRS project, is the emergence of a set of longitudinal studies of aging in other countries which have been consciously designed to produce data as comparable as possible to that collected by the HRS. The HRS provides public use data designed to allow the full power and creativity of America's scientific community to address the challenges of an aging population. The HRS is making a significant impact on research on aging through investigator-initiated research which uses the HRS as an input without charge to researchers or granting agencies.