UNC-Duke Collaborative Clinical Pharmacology Postdoctoral Training Program

 描述(由申请人提供)：北卡罗来纳大学教堂山分校(UNC)与杜克大学(Duke University)和哈姆纳-北卡罗来纳大学药物安全科学研究所(IDSS)合作，拥有成功的临床药理学T32培训计划，该计划以我们独特的研究环境为基础，在药物发现、药物开发、儿科临床药理学、药物基因组学和药物安全方面拥有世界级的计划。我们在临床药理学方面培训临床医生和科学家方面有着出色的记录，并拥有出色的 而多样化的申请者群体中，合格的申请者比有资金的职位多得多。我们在此次续签申请中详细介绍的培训计划提供了强大的领导力、积极参与临床药理学的来自多个学科的国际公认的导师、广泛的尖端技术和资源，以及具有强大机构支持的独特协作环境。该项目的国家申请者来自寻求临床药理学职业道路的医学专业培训项目的医学博士和高级临床/转化性研究培训的药学人员。学员在个性化指导团队的指导下，完成临床药理学课程并参与项目特定活动，以获得当代临床药理学研究的所有方面的专业知识，从药代动力学、药物计量学和药物基因组学到临床试验设计和伦理学。教师导师的选择是基于他们在构成本培训计划核心的四个重点领域中的至少一个领域的研究效率：药物处置和行动；定量药理学和临床试验设计；药物基因组学；药物诱导的器官毒性。这一培训计划的一个独特之处是我们专注于临床药理学中未被研究的领域，特别是儿科和药物安全。我们学员对临床药理学的浓厚兴趣，三所院校在临床药理学研究资源方面的无与伦比的投资，研究三角园区丰富的生物医学科学环境，以及我们长期优秀的研究和培训基础设施，共同创造了临床药理学培训的无与伦比的机会。

 DESCRIPTION (provided by applicant): The University of North Carolina at Chapel Hill (UNC), in collaboration with Duke University and the Hamner-UNC Institute for Drug Safety Sciences (IDSS), has a successful T32 training program in clinical pharmacology that builds on our exceptional research environment with world-class programs in drug discovery, drug development, pediatric clinical pharmacology, pharmacogenomics, and drug safety. We have an outstanding track record of training clinician-scientists in clinical pharmacology and an excellent and diverse applicant pool with many more qualified applicants than funded positions. Our training program detailed in this renewal application offers strong leadership, internationally-recognized mentors from multiple disciplines who are actively involved in clinical pharmacology, a wide-array of cutting edge technologies and resources, and a uniquely collaborative environment with strong institutional support. The national applicant pool for this program is derived both from MDs in medical specialty training programs seeking a career path in clinical pharmacology and PharmDs in advanced clinical/translational research training. Trainees, guided by individualized mentoring teams, complete clinical pharmacology coursework and engage in program-specific activities to gain expertise in all aspects of contemporary clinical pharmacology research, from pharmacokinetics, pharmacometrics and pharmacogenomics to clinical trial design and ethics. Faculty mentors are chosen based on their research productivity in at least one of four focus areas that form the core of this training program: Drug Disposition and Action; Quantitative Pharmacology and Clinical Trial Design; Pharmacogenomics; Drug-induced Organ Toxicity. A unique feature of this training program is our focus on understudied areas in clinical pharmacology, specifically pediatrics and drug safety. The keen interest in clinical pharmacology within our trainee pool, the unparalleled investment in clinical pharmacology research resources at all three institutions, the intellectually-rich biomedical science environment of Research Triangle Park, and our longstanding excellent research and training infrastructure combine to create a moment of unsurpassed opportunity for training in clinical pharmacology.