University Training Program in Biomolecular and Tissue Engineering

描述（由申请人提供）：目前的提案寻求杜克大学生物分子和组织工程（BTE）的NIGMS生物技术培训计划的更新。BTE生物技术培训计划的目标是在生物分子，细胞和组织的设计，操作和定量表征方面提供课堂，实验室和研究博士前培训。BTE的培训项目包括31名培训教师，其中17名来自普拉特工程学院（生物医学工程、土木与环境工程、机械工程与材料科学），14名来自非工程领域的教师。在非工程专业的BTE教师中，有5人在三一文理学院（化学、计算机科学），9人在基础医学（细胞生物学、放射肿瘤学、外科学、生物信息学、医学、眼科和放射学）和杜克大学医学中心临床科室（妇产科学、医学、病理学、放射肿瘤学、放射学、外科学）。17年来，共有68名学生在北京理工大学接受了博士预科培训，其中42人获得了博士学位，18人仍在接受培训，7人已经离开了这个项目。这个

DESCRIPTION (provided by applicant): The current proposal seeks renewal of the NIGMS biotechnology training program in Biomolecular and Tissue Engineering (BTE) at Duke University. The objective of the biotechnology training program in BTE is to provide classroom, laboratory, and research predoctoral training in the design, manipulation, and quantitative characterization of biomolecules, cells and tissues. The training program in BTE involves 31 training faculty with 17 faculty from the Pratt School of Engineering (Biomedical Engineering, Civil & Environmental Engineering, Mechanical Engineering & Materials Science) and 14 faculty from non-engineering fields. Of the non-engineering BTE faculty, 5 are in the Trinity College of Arts & Sciences (Chemistry, Computer Science), and 9 in the Basic Medical Science (Cell Biology, Radiation Oncology, Surgery, Bioinformatics, Medicine, Ophthalmology, and Radiology) and Clinical Departments of the Duke University Medical Center (Obstetrics & Gynecology, Medicine, Pathology, Radiation Oncology, Radiology, Surgery). Over the 17 years of NIGMS support, a total of 68 students have received predoctoral traineeships in BTE: 42 trainees have received their doctorates, 18 are still in training, and 7 have left the program. The disciplinary breakdown of trainees is 47 in BME, 10 in ME&MS, 7 in Chemistry, and 1 each in Biochemical Engineering, Electrical Engineering, Cell Biology, Zoology, and Bioinformatics & Genome Technology. BTE predoctoral trainees are required to (1) perform research that is interdisciplinary in nature and is central to the development of medical biotechnology, (2) have at least two BTE faculty on their doctoral dissertation committee, (3) take one of three approved laboratory-based engineering courses in modern biotechnology, (4) take four engineering electives that provide breadth in BTE [trainees entering the program from non-engineering disciplines select two engineering electives], (5) take two advanced courses in the biomedical sciences relevant to BTE, (6) take two semesters of the interdisciplinary "BioE" seminar series for credit, (7) participate in a three-month industrial biotechnology internship, (8) present in th annual BTE poster session, and (9) undergo training in responsible conduct in research. The BTE training grant currently supports 9 fellows for two years commencing in either the first or second year of graduate study. We request that this level of support be maintained.