Phosphatase regulators mediate long-term changes in presynaptic terminals

磷酸酶调节剂介导突触前末梢的长期变化

• 批准号: nhmrc : GNT1079160
• 负责人: Dr Mark Graham
• 金额: $ 94.28万
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2015
• 资助国家: 澳大利亚
• 起止时间: 2015-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/phosphatase-regulators-mediate-presynaptic-terminals/1345260
• 关键词: Phosphatase; regulators; mediate; long; term

The strength of communication between each nerve cell in the brain depends on how active that nerve cell has been. This enables the brain to be adaptable and is a way for the brain to set up circuits that underlie how we learn and remember. More or less release of chemical messengers (neurotransmitters) into nerve cell junctions changes the strength of nerve cell communication. We have discovered a new chemical signalling pathway controlling neurotransmitter release.

大脑中每个神经细胞之间的交流强度取决于该神经细胞的活跃程度。这使大脑具有适应性，是大脑建立回路的一种方式，这些回路是我们学习和记忆的基础。化学信使（神经递质）或多或少地释放到神经细胞连接处会改变神经细胞通讯的强度。我们发现了一种新的控制神经递质释放的化学信号通路。