Mechanisms of synaptic vesicle endocytosis revealed by its regulatory phosphoproteome
Mechanisms of synaptic vesicle endocytosis revealed by its regulatory phosphoproteome
批准号:
nhmrc : 571070
负责人:
Dr Mark Graham
金额:
$36.36万
依托单位:
依托单位国家:
澳大利亚
项目类别:
NHMRC Project Grants
财政年份:
2009
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2009-01-01 至 2012-12-31
中文摘要
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英文摘要
The nerve cells in our brains are in constant communication to sustain life. Communication involves electrical stimulation of one nerve cell which then responds by releasing chemical messengers, from vesicles, onto the next cell. Our research focuses on the mechanism of recycling of vesicles. Targeting this mechanism is a way to gain fundamental knowledge of how to intervene medically when communication fails, or when communication needs to be dampened, such as in some neurological diseases.
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To investigate the role of ATM protein in protecting against neurodegeneration
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批准号:nhmrc : 1077989
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项目类别:Project Grants
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资助金额:$63.59万
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财政年份:2015
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负责人:Dr Mark Graham
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依托单位:
Phosphatase regulators mediate long-term changes in presynaptic terminals
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批准号:nhmrc : 1079160
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项目类别:Project Grants
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资助金额:$65.62万
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财政年份:2015
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负责人:Dr Mark Graham
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依托单位:
Phosphatase regulators mediate long-term changes in presynaptic terminals
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批准号:nhmrc : GNT1079160
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项目类别:Project Grants
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资助金额:$94.28万
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财政年份:2015
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负责人:Dr Mark Graham
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依托单位:
To investigate the role of ATM protein in protecting against neurodegeneration
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批准号:nhmrc : GNT1077989
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项目类别:Project Grants
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资助金额:$92.08万
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财政年份:2015
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负责人:Dr Mark Graham
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依托单位:
Phosphorylation of synaptic vesicle glycoprotein 2 (SV2) regulates endocytosis of synaptotagmin for synaptic transmission
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批准号:nhmrc : 1052494
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项目类别:Project Grants
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资助金额:$40.9万
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财政年份:2013
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负责人:Dr Mark Graham
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依托单位:
Role of oxidative stress in activating ATM to protect against neurodegeneration
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批准号:nhmrc : 1019996
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项目类别:Project Grants
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资助金额:$38.03万
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财政年份:2012
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负责人:Dr Mark Graham
-
依托单位:
ATM Activation and its functional Importance in DNA damage response
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批准号:nhmrc : 569591
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项目类别:NHMRC Project Grants
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资助金额:$37.04万
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财政年份:2009
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负责人:Dr Mark Graham
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依托单位:
Inhibitory signalling switches define the machinery of synaptic vesicle endocytosis
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批准号:nhmrc : 531700
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项目类别:Career Development Fellowships
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资助金额:$25.84万
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财政年份:2009
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负责人:Dr Mark Graham
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依托单位:
O-GlcNAc-phosphorylation: a novel post-translational modification regulating vesicle recycling.
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批准号:DP0987706
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项目类别:Discovery Projects
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资助金额:$20.8万
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财政年份:2009
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负责人:Dr Mark Graham
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依托单位:
国内基金
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