Inhibitory signalling switches define the machinery of synaptic vesicle endocytosis

为了维持生命，我们大脑中的神经细胞不断地进行交流。通讯涉及一个神经细胞通过将化学信使从小泡释放到下一个细胞来对电刺激做出反应。我们的研究重点是囊泡再循环的机制。以这种机制为目标是一种获得基本知识的方法，即在神经系统疾病中，当沟通失败时，或当沟通需要抑制时，如何进行医学干预。

The nerve cells in our brains are in constant communication to sustain life. Communication involves one nerve cell responding to electrical stimulation by releasing chemical messengers, from vesicles, onto the next cell. Our research focuses on the mechanism of recycling of vesicles. Targeting this mechanism is a way to gain fundamental knowledge of how to intervene medically when communication fails, or when communication needs to be dampened, in neurological diseases.