Receptor tyrosine kinase function as molecular target in cancer.
Receptor tyrosine kinase function as molecular target in cancer.
批准号:
nhmrc : 1003908
负责人:
A/Pr Martin Lackmann
金额:
$27.72万
依托单位:
依托单位国家:
澳大利亚
项目类别:
NHMRC Research Fellowships
财政年份:
2011
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2011-01-01 至 2014-12-31
中文摘要
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英文摘要
As molecular cell biologist and protein chemist my motivation for research is to tackle metastatic cancer, one of the principle health burdens of the 21 century. Over the next five years I will lead R&D programs with national and international collaborators that will generate new diagnostic approaches and insights in basic and translational research. These will allow us to develop anti-cancer drugs, which target several of the mechanisms that are active in metastatic cancers.
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会议论文
Antibody-based inhibition of ADAM10 as cancer immunotherapy
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批准号:nhmrc : 1067609
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项目类别:Project Grants
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资助金额:$43.53万
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财政年份:2014
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负责人:A/Pr Martin Lackmann
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依托单位:
Control of gastrointestinal tumour progression by therapeutic interference with myeloid derived cells
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批准号:nhmrc : 1067244
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项目类别:Project Grants
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资助金额:$50.59万
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财政年份:2014
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负责人:A/Pr Martin Lackmann
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依托单位:
Can inhibition of myeloid cell function suppress gastro-intestinal cancer?
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批准号:nhmrc : GNT1067244
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项目类别:Project Grants
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资助金额:$72.75万
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财政年份:2014
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负责人:A/Pr Martin Lackmann
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依托单位:
Inhibiting tumour growth by targeting EphA3 and disrupting tumour stromal and vascular microenvironment
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批准号:nhmrc : 1049942
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项目类别:Project Grants
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资助金额:$43.02万
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财政年份:2013
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负责人:A/Pr Martin Lackmann
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依托单位:
The role of protein tyrosine phosphatases regulating Eph RTK-signalling and modulating invasive tumour cell properties.
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批准号:nhmrc : 436774
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项目类别:NHMRC Project Grants
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资助金额:$20.26万
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财政年份:2007
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负责人:A/Pr Martin Lackmann
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依托单位:
EphA3-modulated cell positioning in tumour invasion and neovascularisation.
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批准号:nhmrc : 384241
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项目类别:NHMRC Project Grants
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资助金额:$43.16万
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财政年份:2006
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负责人:A/Pr Martin Lackmann
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依托单位:
Research Fellowship - Grant ID:384113
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批准号:nhmrc : 384113
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项目类别:NHMRC Research Fellowships
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资助金额:$36.6万
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财政年份:2006
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负责人:A/Pr Martin Lackmann
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依托单位:
Functional analysis of the molecular switch that regulates ADAM10-mediated cleavage of RTK ligands in tumour cells.
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批准号:nhmrc : 384242
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项目类别:NHMRC Project Grants
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资助金额:$30.49万
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财政年份:2006
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负责人:A/Pr Martin Lackmann
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依托单位:
The Role of Eph/ephrin clustering and trafficking in control of tumour cell invasion
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批准号:nhmrc : 334085
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项目类别:NHMRC Project Grants
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资助金额:$29.31万
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财政年份:2005
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负责人:A/Pr Martin Lackmann
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依托单位:
Stage II in the development of Eph/ephrin based tumor targeting reagents: Optimisation of drug efficacy and delivery
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批准号:nhmrc : 284418
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项目类别:NHMRC Development Grants
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资助金额:$13.61万
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财政年份:2004
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负责人:A/Pr Martin Lackmann
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依托单位:
Development of anti-metastatic and tumour targeting reagents by design of inhibitors to specific Eph/ephrin cell-cell
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批准号:nhmrc : 234712
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项目类别:NHMRC Development Grants
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资助金额:$13.34万
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财政年份:2003
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负责人:A/Pr Martin Lackmann
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依托单位:
Development and evaluation of biological reagents targeting and inhibiting function of the EphA3 receptor on tumor cells
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批准号:nhmrc : 234707
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项目类别:NHMRC Project Grants
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资助金额:$32.71万
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财政年份:2003
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负责人:A/Pr Martin Lackmann
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依托单位:
Signal transduction pathways of EphA receptor tyrosine kinases
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批准号:nhmrc : 991280
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项目类别:NHMRC Project Grants
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资助金额:$12.15万
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财政年份:1999
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负责人:A/Pr Martin Lackmann
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依托单位:
国内基金
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批准号:30971223
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项目类别:面上项目
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资助金额:17.0万元
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批准年份:2007
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负责人:段春礼
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依托单位: