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Stage II in the development of Eph/ephrin based tumor targeting reagents: Optimisation of drug efficacy and delivery

Stage II in the development of Eph/ephrin based tumor targeting reagents: Optimisation of drug efficacy and delivery
基于 Eph/ephrin 的肿瘤靶向试剂开发的第二阶段:药物功效和递送的优化
批准号:
nhmrc : 284418
负责人:
A/Pr Martin Lackmann
金额:
$13.61万
依托单位:
依托单位国家:
澳大利亚
项目类别:
NHMRC Development Grants
财政年份:
2004
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2004-01-01 至 2005-12-31

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英文摘要
In the final stage of cancer, including melanoma, tumor cells gain the ability to spread, a process called metastasis. Altered communication between cancer and normal cells is one of the causes of this invasive characteristic. We have started the development of novel agents that target and modulate proteins on the cell surface that control these properties and are found in metastatic tumors. We propose to refine the targeting and killing properties of these agents for early clinical testing.
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