Targeting the insulin and insulin-like growth factor receptors in cancer, diabetes and Alzheimer's disease

靶向癌症、糖尿病和阿尔茨海默病中的胰岛素和胰岛素样生长因子受体

• 批准号: nhmrc : 1058233
• 负责人: A/Pr Michael Lawrence
• 金额: $ 66.23万
• 依托单位: The Walter and Eliza Hall Institute of Medical Research
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2014
• 资助国家: 澳大利亚
• 起止时间: 2014-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/targeting-insulin-insulin-alzheimers-disease/454660
• 关键词: Targeting; insulin; like; growth; factor

Diabetes, cancer and Alzheimer's disease are three major diseases facing Australia. This Project will investigate a common point-of-focus of these diseases, namely the interaction of insulin and the insulin-like growth factors with their receptor molecules on the cell surface. It will use recent breakthrough findings by the Chief Investigators to develop new therapeutic approaches for these diseases that could function by targeting these interactions.

糖尿病、癌症和阿尔茨海默病是澳大利亚面临的三大疾病。本项目将研究这些疾病的一个共同焦点，即胰岛素和胰岛素样生长因子与其细胞表面受体分子的相互作用。它将利用首席调查人员最近的突破性发现，为这些疾病开发新的治疗方法，这些方法可以通过针对这些相互作用发挥作用。