Structural Basis of Ligand Binding to Type 1 Insulin-like Growth Factor Receptor (IGF-1R)
Structural Basis of Ligand Binding to Type 1 Insulin-like Growth Factor Receptor (IGF-1R)
批准号:
nhmrc : 575539
负责人:
A/Pr Michael Lawrence
金额:
$29.78万
依托单位国家:
澳大利亚
项目类别:
NHMRC Project Grants
财政年份:
2009
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2009-01-01 至 2011-12-31
中文摘要
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英文摘要
Insulin-like growth factors are involved in normal growth and development. However, they are also implicated in cancer development and progression. We are seeking to understand the way in which these growth factors bind to their receptor on the surface of the cell and stimulate the cell to survive, proliferate and migrate to new tumour sites. Such knowledge will be useful in the design of molecules that could potentially intervere with this process and thus be used as anti-cancer therapeutics.
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依托单位:
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