Translating the genetic determinants of glaucoma

转化青光眼的遗传决定因素

• 批准号: nhmrc : GNT1154543
• 负责人: A/Pr Stuart Macgregor
• 金额: $ 64.92万
• 依托单位国家: 澳大利亚
• 项目类别: Research Fellowships
• 财政年份: 2019
• 资助国家: 澳大利亚
• 起止时间: 2019-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/translating-genetic-determinants-glaucoma/1349147
• 关键词: Translating; genetic; determinants; glaucoma

Glaucoma is the leading cause of irreversible blindness worldwide. In Australia the total cost of glaucoma will exceed $4.3 billion per annum by 2027. Reducing the disease burden depends critically upon leveraging genetic information. I will expand our knowledge of the genes responsible for glaucoma and develop an evidence base for incorporating genetic testing into clinical practice. This will reduce monitoring costs in low risk individuals and reduce blindness in high risk individuals.

青光眼是世界范围内不可逆性失明的主要原因。在澳大利亚，到2027年，青光眼的总成本将超过每年43亿美元。减少疾病负担关键取决于利用遗传信息。我将扩大我们对青光眼基因的了解，并为将基因检测纳入临床实践建立证据基础。这将降低低风险个体的监测成本，并减少高风险个体的失明。