Understanding whole cell protein trafficking in Plasmodium parasites

了解疟原虫寄生虫中的全细胞蛋白质运输

• 批准号: nhmrc : 1062504
• 负责人: A/Pr Stuart Ralph
• 金额: $ 31.11万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Career Development Fellowships
• 财政年份: 2014
• 资助国家: 澳大利亚
• 起止时间: 2014-01-01 至 2017-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/understanding-cell-protein-plasmodium-parasites/454997
• 关键词: Understanding; whole; cell; protein; trafficking

I am a molecular biologist and bioinformatician studying the cell biology of human parasites. I have expertise in the bioinformatic analysis of parasite genomes to predict where proteins will reside in cell, how they participate in metabolic pathways, and how they might be suitable as targets for drugs and vaccines to control parasitic diseases. This fellowship will investigate the cell biology of Plasmodium parasites, the causative agents of malaria, using computational and biochemical tools to characterise drug and vaccine targets.

我是一名分子生物学家和生物信息学家，研究人类寄生虫的细胞生物学。我在寄生虫基因组的生物信息学分析方面具有专业知识，可以预测蛋白质在细胞中的位置，它们如何参与代谢途径，以及它们如何适合作为药物和疫苗的靶点来控制寄生虫病。这项研究将调查疟原虫寄生虫的细胞生物学，疟疾的病原体，使用计算和生物化学工具，以确定药物和疫苗的目标。