Molecular basis of artemisinin action and resistance in Plasmodium falciparum
Molecular basis of artemisinin action and resistance in Plasmodium falciparum
批准号:
nhmrc : GNT1139884
负责人:
A/Pr Stuart Ralph
金额:
$75.85万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2018
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2018-01-01 至 --
中文摘要
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英文摘要
The malaria parasite, P. falciparum causes ~450,000 deaths each year. Resistance to the front-line antimalarial drug, artemisinin, is increasing, threatening at least another 100,000 lives per year, and potentially causing an additional ~A$500M in lost productivity. This project will identify the components of the parasite's cellular defence system that underpin resistance and will point to strategies for overcoming resistance to this important drug class.
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Molecular basis of artemisinin action and resistance in Plasmodium falciparum
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批准号:nhmrc : 1139884
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项目类别:Project Grants
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资助金额:$51.28万
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财政年份:2018
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负责人:A/Pr Stuart Ralph
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依托单位:
Cell biology of malaria parasites
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批准号:nhmrc : GNT1062504
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项目类别:Career Development Fellowships
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资助金额:$44.78万
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财政年份:2014
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负责人:A/Pr Stuart Ralph
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依托单位:
Understanding whole cell protein trafficking in Plasmodium parasites
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批准号:nhmrc : 1062504
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项目类别:Career Development Fellowships
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资助金额:$31.11万
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财政年份:2014
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负责人:A/Pr Stuart Ralph
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依托单位:
Cytoskeletal remodeling of the erythrocyte during malaria parasite invasion
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批准号:nhmrc : 1047085
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项目类别:Project Grants
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资助金额:$37.33万
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财政年份:2013
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负责人:A/Pr Stuart Ralph
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依托单位:
Metabolomic analysis of Plasmodum falciparum and mode of action of antimalarial compounds
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批准号:nhmrc : 1006024
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项目类别:Project Grants
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资助金额:$61.16万
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财政年份:2011
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负责人:A/Pr Stuart Ralph
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依托单位:
Cytosolic and organellar tRNA synthetases in Plasmodium falciparum
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批准号:nhmrc : 628704
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项目类别:NHMRC Project Grants
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资助金额:$28.29万
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财政年份:2010
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负责人:A/Pr Stuart Ralph
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依托单位:
Dissecting the Molecular Basis of the Malaria Parasite-Erythrocyte Tight Junction Complex
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批准号:nhmrc : 637340
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项目类别:NHMRC Project Grants
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资助金额:$36.5万
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财政年份:2010
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负责人:A/Pr Stuart Ralph
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依托单位:
Targeting Protein Synthesis in the Apicoplast and Cytoplasm of Plasmodium
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批准号:nhmrc : 520700
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项目类别:NHMRC Strategic Awards
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资助金额:$30.26万
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财政年份:2010
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负责人:A/Pr Stuart Ralph
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依托单位:
Epigenetic control of antigenic variation in Plasmodium falciparum
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批准号:nhmrc : 461231
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项目类别:NHMRC Project Grants
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资助金额:$33.71万
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财政年份:2007
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负责人:A/Pr Stuart Ralph
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依托单位:
Antigenic variation in Plasmodium falciparum
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批准号:nhmrc : 251775
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项目类别:Early Career Fellowships
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资助金额:$25.52万
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财政年份:2003
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负责人:A/Pr Stuart Ralph
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依托单位:
国内基金
海外基金
基于Volatility Basis-set方法对上海大气二次有机气溶胶生成的模拟
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批准号:41105102
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项目类别:青年科学基金项目
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资助金额:24.0万元
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批准年份:2011
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负责人:王杨君
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依托单位:
求解Basis Pursuit问题的数值优化方法
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批准号:11001128
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项目类别:青年科学基金项目
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资助金额:18.0万元
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批准年份:2010
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负责人:王丽平
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依托单位:
TB方法在有机和生物大分子体系计算研究中的应用
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批准号:20773047
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项目类别:面上项目
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资助金额:26.0万元
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批准年份:2007
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负责人:吕文彩
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依托单位: