Cytosolic and organellar tRNA synthetases in Plasmodium falciparum
Cytosolic and organellar tRNA synthetases in Plasmodium falciparum
批准号:
nhmrc : 628704
负责人:
A/Pr Stuart Ralph
金额:
$28.29万
依托单位国家:
澳大利亚
项目类别:
NHMRC Project Grants
财政年份:
2010
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2010-01-01 至 2013-12-31
中文摘要
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英文摘要
Malaria is a major worldwide infectious disease. The disease kills around 2 million people every year, and current drugs are increasingly failing due to parasite drug resistance, creating an urgent demand for new drugs, that inhibit different targets. I will study a new class of parasite drug targets, the tRNA synthetase enzymes to find novel inhibitors. Compounds blocking these enzymes may lead to new drugs to combat malaria.
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会议论文
Molecular basis of artemisinin action and resistance in Plasmodium falciparum
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批准号:nhmrc : GNT1139884
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项目类别:Project Grants
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资助金额:$75.85万
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财政年份:2018
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负责人:A/Pr Stuart Ralph
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依托单位:
Molecular basis of artemisinin action and resistance in Plasmodium falciparum
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批准号:nhmrc : 1139884
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项目类别:Project Grants
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资助金额:$51.28万
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财政年份:2018
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负责人:A/Pr Stuart Ralph
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依托单位:
Cell biology of malaria parasites
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批准号:nhmrc : GNT1062504
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项目类别:Career Development Fellowships
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资助金额:$44.78万
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财政年份:2014
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负责人:A/Pr Stuart Ralph
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依托单位:
Understanding whole cell protein trafficking in Plasmodium parasites
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批准号:nhmrc : 1062504
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项目类别:Career Development Fellowships
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资助金额:$31.11万
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财政年份:2014
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负责人:A/Pr Stuart Ralph
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依托单位:
Cytoskeletal remodeling of the erythrocyte during malaria parasite invasion
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批准号:nhmrc : 1047085
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项目类别:Project Grants
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资助金额:$37.33万
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财政年份:2013
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负责人:A/Pr Stuart Ralph
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依托单位:
Metabolomic analysis of Plasmodum falciparum and mode of action of antimalarial compounds
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批准号:nhmrc : 1006024
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项目类别:Project Grants
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资助金额:$61.16万
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财政年份:2011
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负责人:A/Pr Stuart Ralph
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依托单位:
Dissecting the Molecular Basis of the Malaria Parasite-Erythrocyte Tight Junction Complex
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批准号:nhmrc : 637340
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项目类别:NHMRC Project Grants
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资助金额:$36.5万
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财政年份:2010
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负责人:A/Pr Stuart Ralph
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依托单位:
Targeting Protein Synthesis in the Apicoplast and Cytoplasm of Plasmodium
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批准号:nhmrc : 520700
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项目类别:NHMRC Strategic Awards
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资助金额:$30.26万
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财政年份:2010
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负责人:A/Pr Stuart Ralph
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依托单位:
Epigenetic control of antigenic variation in Plasmodium falciparum
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批准号:nhmrc : 461231
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项目类别:NHMRC Project Grants
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资助金额:$33.71万
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财政年份:2007
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负责人:A/Pr Stuart Ralph
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依托单位:
Antigenic variation in Plasmodium falciparum
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批准号:nhmrc : 251775
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项目类别:Early Career Fellowships
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资助金额:$25.52万
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财政年份:2003
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负责人:A/Pr Stuart Ralph
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依托单位:
海外基金