Vesicular trafficking in neurons in health and disease
Vesicular trafficking in neurons in health and disease
批准号:
nhmrc : GNT1060075
负责人:
Prof Frederic Meunier
金额:
$66.45万
依托单位国家:
澳大利亚
项目类别:
Research Fellowships
财政年份:
2014
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2014-01-01 至 --
中文摘要
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英文摘要
Plethora of diseases of the nervous system are caused by defects in vesicular trafficking including neurodegenerative diseases such as Alzheimer’s disease. I will explore the mechanisms underpinning synaptic vesicular trafficking using novel super resolution techniques and reveal the how secretory vesicles traffic to the plasma membrane, undergo exocytosis, and recycle. I will also explain how in the crowded environment of the presynaptic terminals, retrograde cargoes are transported back to the cell body thereby carrying survival signals.
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Nanoscale imaging of presynaptic proteins in health and disease
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批准号:nhmrc : GNT1155794
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项目类别:Research Fellowships
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财政年份:2019
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依托单位:
Unveiling the nanoscale organisation and dynamics of synaptic vesicle pools
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批准号:DP190100674
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项目类别:Discovery Projects
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资助金额:$46.91万
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财政年份:2019
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负责人:Prof Frederic Meunier
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依托单位:
TAU AND ITS MASTER REGULATOR FYN IN NEURONS
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批准号:nhmrc : 1127999
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项目类别:Project Grants
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资助金额:$51.77万
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财政年份:2017
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负责人:Prof Frederic Meunier
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依托单位:
TAU AND ITS MASTER REGULATOR FYN IN NEURONS
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批准号:nhmrc : GNT1127999
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项目类别:Project Grants
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资助金额:$75.87万
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财政年份:2017
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负责人:Prof Frederic Meunier
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依托单位:
Unravelling a new fatty acid pathway involved in neuroexocytosis and memory
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批准号:nhmrc : 1120374
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项目类别:Project Grants
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资助金额:$36.85万
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财政年份:2017
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负责人:Prof Frederic Meunier
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依托单位:
Intra and intermolecular steps underpinning vesicular priming
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批准号:DP170100125
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项目类别:Discovery Projects
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资助金额:$38.52万
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财政年份:2017
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负责人:Prof Frederic Meunier
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依托单位:
Unravelling the mechanism of vesicular docking in neurosecretory cells
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批准号:DP150100539
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项目类别:Discovery Projects
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资助金额:$30.03万
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财政年份:2015
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负责人:Prof Frederic Meunier
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依托单位:
Vesicular trafficking pathways underpinning neuronal secretion and survival
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批准号:nhmrc : 1060075
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项目类别:Research Fellowships
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资助金额:$46.49万
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财政年份:2014
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负责人:Prof Frederic Meunier
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依托单位:
Live molecular imaging using super resolution microscopy, two photon and spinning disk confocal microscopy
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批准号:LE130100078
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项目类别:Linkage Infrastructure, Equipment and Facilities
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资助金额:$53.34万
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财政年份:2013
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负责人:Prof Frederic Meunier
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依托单位:
The role of actin in driving bulk endocytosis in neurons and neurosecretory cells
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批准号:DP120104057
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项目类别:Discovery Projects
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资助金额:$26.98万
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财政年份:2012
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负责人:Prof Frederic Meunier
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依托单位:
Modulating neuronal secretion by the PI3-kinase pathway
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批准号:nhmrc : 631568
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项目类别:NHMRC Project Grants
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资助金额:$34.46万
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财政年份:2010
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负责人:Prof Frederic Meunier
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依托单位:
Sustaining neuronal communication through bulk endocytosis
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批准号:DP0987669
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项目类别:Discovery Projects
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资助金额:$18.6万
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财政年份:2009
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负责人:Prof Frederic Meunier
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依托单位:
Uncoupled Research Fellowship
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批准号:nhmrc : 569596
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项目类别:NHMRC Research Fellowships
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资助金额:$38.72万
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财政年份:2009
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负责人:Prof Frederic Meunier
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依托单位:
High Speed Fluorescence Imaging coupled with Total Internal Reflection Microscopy and Fluorescence Recovery After Photobleaching System
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批准号:LE0882864
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项目类别:Linkage Infrastructure, Equipment and Facilities
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资助金额:$17.34万
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财政年份:2008
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负责人:Prof Frederic Meunier
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依托单位:
Deciphering the molecular steps leading to the potentiation of neuronal exocytosis by arachidonic acid
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批准号:nhmrc : 351434
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项目类别:NHMRC Project Grants
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资助金额:$18.2万
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财政年份:2005
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负责人:Prof Frederic Meunier
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依托单位:
Glycerotoxin, a unique tool to investigate the dynamic interactions between N-type Ca2+ channels and the exo-endocytic machinery
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批准号:DP0452106
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项目类别:Discovery Projects
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资助金额:$18.8万
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财政年份:2004
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负责人:Prof Frederic Meunier
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依托单位:
Role of 3'-phosphorylated phosphoinositides in neurosecretion
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批准号:DP0449683
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项目类别:Discovery Projects
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资助金额:$16.71万
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财政年份:2004
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负责人:Prof Frederic Meunier
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依托单位:
国内基金
海外基金
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