Unravelling a new fatty acid pathway involved in neuroexocytosis and memory

揭示涉及神经胞吐作用和记忆的新脂肪酸途径

• 批准号: nhmrc : 1120374
• 负责人: Prof Frederic Meunier
• 金额: $ 36.85万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2017
• 资助国家: 澳大利亚
• 起止时间: 2017-01-01 至 2019-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/unravelling-new-fatty-neuroexocytosis-memory/946516
• 关键词: Unravelling; new; fatty; acid; pathway

This proposal build on the establishment by our laboratory of the assay capable of detecting free fatty acids, with great accuracy and sensitivity. Using this assay we have uncovered a completely new pathway highlighting the production of saturated free fatty acids linked to learning and memory. We will fully define how this pathway is regulated in the brain.

本建议建立在我们实验室建立的能够检测游离脂肪酸的测定方法的基础上，具有很高的准确性和灵敏度。通过这项实验，我们发现了一条全新的途径，强调与学习和记忆有关的饱和游离脂肪酸的产生。我们将完全确定这条通路在大脑中是如何被调节的。