TAU AND ITS MASTER REGULATOR FYN IN NEURONS
TAU AND ITS MASTER REGULATOR FYN IN NEURONS
批准号:
nhmrc : 1127999
负责人:
Prof Frederic Meunier
金额:
$51.77万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2017
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2017-01-01 至 2019-12-31
中文摘要
点击翻译按钮获取中文摘要
英文摘要
Neurons are highly compartmentalized cell-types. In neurodegenerative diseases such as Alzheimer's disease, the protein Tau that serves a distinct function in one cellular compartment (the axon) accumulates in a massively phosphorylated form elsewhere (somatodendritic compartments and their spines) which is believed to impair neuronal functions. We will investigate how Tau is distributed in health and disease, and determine how this distribution is regulated.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Role of Tau and Synapsin in clustering distinct synaptic vesicle pools
-
批准号:DP230102278
-
项目类别:Discovery Projects
-
资助金额:$33.68万
-
财政年份:2023
-
负责人:Prof Frederic Meunier
-
依托单位:
Super-resolving neurotransmitter release machinery during priming
-
批准号:DP220102334
-
项目类别:Discovery Projects
-
资助金额:$41.33万
-
财政年份:2022
-
负责人:Prof Frederic Meunier
-
依托单位:
Nanoscale imaging of presynaptic proteins in health and disease
-
批准号:nhmrc : GNT1155794
-
项目类别:Research Fellowships
-
资助金额:$71.73万
-
财政年份:2019
-
负责人:Prof Frederic Meunier
-
依托单位:
Unveiling the nanoscale organisation and dynamics of synaptic vesicle pools
-
批准号:DP190100674
-
项目类别:Discovery Projects
-
资助金额:$46.91万
-
财政年份:2019
-
负责人:Prof Frederic Meunier
-
依托单位:
TAU AND ITS MASTER REGULATOR FYN IN NEURONS
-
批准号:nhmrc : GNT1127999
-
项目类别:Project Grants
-
资助金额:$75.87万
-
财政年份:2017
-
负责人:Prof Frederic Meunier
-
依托单位:
Unravelling a new fatty acid pathway involved in neuroexocytosis and memory
-
批准号:nhmrc : 1120374
-
项目类别:Project Grants
-
资助金额:$36.85万
-
财政年份:2017
-
负责人:Prof Frederic Meunier
-
依托单位:
Intra and intermolecular steps underpinning vesicular priming
-
批准号:DP170100125
-
项目类别:Discovery Projects
-
资助金额:$38.52万
-
财政年份:2017
-
负责人:Prof Frederic Meunier
-
依托单位:
Unravelling the mechanism of vesicular docking in neurosecretory cells
-
批准号:DP150100539
-
项目类别:Discovery Projects
-
资助金额:$30.03万
-
财政年份:2015
-
负责人:Prof Frederic Meunier
-
依托单位:
Vesicular trafficking pathways underpinning neuronal secretion and survival
-
批准号:nhmrc : 1060075
-
项目类别:Research Fellowships
-
资助金额:$46.49万
-
财政年份:2014
-
负责人:Prof Frederic Meunier
-
依托单位:
Vesicular trafficking in neurons in health and disease
-
批准号:nhmrc : GNT1060075
-
项目类别:Research Fellowships
-
资助金额:$66.45万
-
财政年份:2014
-
负责人:Prof Frederic Meunier
-
依托单位:
Live molecular imaging using super resolution microscopy, two photon and spinning disk confocal microscopy
-
批准号:LE130100078
-
项目类别:Linkage Infrastructure, Equipment and Facilities
-
资助金额:$53.34万
-
财政年份:2013
-
负责人:Prof Frederic Meunier
-
依托单位:
The role of actin in driving bulk endocytosis in neurons and neurosecretory cells
-
批准号:DP120104057
-
项目类别:Discovery Projects
-
资助金额:$26.98万
-
财政年份:2012
-
负责人:Prof Frederic Meunier
-
依托单位:
Modulating neuronal secretion by the PI3-kinase pathway
-
批准号:nhmrc : 631568
-
项目类别:NHMRC Project Grants
-
资助金额:$34.46万
-
财政年份:2010
-
负责人:Prof Frederic Meunier
-
依托单位:
Sustaining neuronal communication through bulk endocytosis
-
批准号:DP0987669
-
项目类别:Discovery Projects
-
资助金额:$18.6万
-
财政年份:2009
-
负责人:Prof Frederic Meunier
-
依托单位:
Uncoupled Research Fellowship
-
批准号:nhmrc : 569596
-
项目类别:NHMRC Research Fellowships
-
资助金额:$38.72万
-
财政年份:2009
-
负责人:Prof Frederic Meunier
-
依托单位:
High Speed Fluorescence Imaging coupled with Total Internal Reflection Microscopy and Fluorescence Recovery After Photobleaching System
-
批准号:LE0882864
-
项目类别:Linkage Infrastructure, Equipment and Facilities
-
资助金额:$17.34万
-
财政年份:2008
-
负责人:Prof Frederic Meunier
-
依托单位:
Deciphering the molecular steps leading to the potentiation of neuronal exocytosis by arachidonic acid
-
批准号:nhmrc : 351434
-
项目类别:NHMRC Project Grants
-
资助金额:$18.2万
-
财政年份:2005
-
负责人:Prof Frederic Meunier
-
依托单位:
Glycerotoxin, a unique tool to investigate the dynamic interactions between N-type Ca2+ channels and the exo-endocytic machinery
-
批准号:DP0452106
-
项目类别:Discovery Projects
-
资助金额:$18.8万
-
财政年份:2004
-
负责人:Prof Frederic Meunier
-
依托单位:
Role of 3'-phosphorylated phosphoinositides in neurosecretion
-
批准号:DP0449683
-
项目类别:Discovery Projects
-
资助金额:$16.71万
-
财政年份:2004
-
负责人:Prof Frederic Meunier
-
依托单位:
国内基金
海外基金
登录
查看更多内容
Accretion variability and its consequences: from protostars to planet-forming disks
-
批准号:12173003
-
项目类别:面上项目
-
资助金额:60万元
-
批准年份:2021
-
负责人:沈雷歌
-
依托单位:
ITS2“分类阈值”的构建及其在混合中药材高通量鉴定中的应用基础
-
批准号:U2106227
-
项目类别:面上项目
-
资助金额:55万元
-
批准年份:2021
-
负责人:张伟
-
依托单位:
核糖体ITS2前体rRNA加工的作用机理研究
-
批准号:32171286
-
项目类别:面上项目
-
资助金额:58万元
-
批准年份:2021
-
负责人:刘亮
-
依托单位:
土壤微生物残留rDNA和ITS的类群特异性降解速率研究
-
批准号:42007035
-
项目类别:青年科学基金项目
-
资助金额:24.0万元
-
批准年份:2020
-
负责人:车荣晓
-
依托单位:
基于ITS探讨软骨下骨rod-plate微结构重塑在骨关节炎发病机制中的作用
-
批准号:81601930
-
项目类别:青年科学基金项目
-
资助金额:18.0万元
-
批准年份:2016
-
负责人:陈炎
-
依托单位:
ITS-HPLC-HRMS-Bioassay多级筛选策略指导下海洋真菌中新型抗菌活性产物的发现
-
批准号:41606166
-
项目类别:青年科学基金项目
-
资助金额:20.0万元
-
批准年份:2016
-
负责人:彭吉星
-
依托单位:
ITS2二级结构的系统发育信息在药用植物DNA条形码中的应用价值研究
-
批准号:81673551
-
项目类别:面上项目
-
资助金额:57.0万元
-
批准年份:2016
-
负责人:张伟
-
依托单位:
ITS融合型新一代混合动力汽车的几个关键控制问题研究
-
批准号:61573304
-
项目类别:面上项目
-
资助金额:66.0万元
-
批准年份:2015
-
负责人:焦晓红
-
依托单位:
丝状子囊菌ITS分子进化研究
-
批准号:31400018
-
项目类别:青年科学基金项目
-
资助金额:24.0万元
-
批准年份:2014
-
负责人:李熠
-
依托单位:
基于ITS2互补碱基变化分析的中药基原物种鉴定研究
-
批准号:81373922
-
项目类别:面上项目
-
资助金额:70.0万元
-
批准年份:2013
-
负责人:宋经元
-
依托单位: