Plasma Enhanced CVD System for Polymer Coating Deposition on Tubular Tiny Medical Devices

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Cardiovascular stents are small devices inserted into blood vessels to prevent localized flow restriction due to vascular diseases. Unfortunately, failure or clinical complications are often observed with the current commercial devices. Therefore, the proposed project focuses on designing an innovative functional material for surface modification of stents. Furthermore, the process is designed to be easily transferable to a number of biomedical applications where functional coatings seek to improve clinical performances. More precisely, our aim is to design surface modifications allowing the development of polymer-based highly adherent and cohesive nano-coatings for stents. Polymer coatings are potential solutions for locally controlled drug release and they can also act as barrier for potentially toxic metallic ions release by metallic stents. Moreover, they can be used as carriers to graft biomolecules that are largely studied to improve the interaction of materials with the biological system. A challenging task is to coat materials with complex geometries like stents and to determine their mechanical and biological performances. Overall, these new nano-coatings should contribute to improve the clinical performances of stents and therefore impact positively the quality and cost of healthcare in Canada and around the globe.